2'-Chloro-4,4'-difluorochalcone
TL;DR: 2'-Chloro-4,4'-difluorochalcone (CAS 7394-01-6) is a chemical compound with molecular formula C15H9ClF2O and molecular weight 278.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(2-chloro-4-fluorophenyl)-1-(4-fluorophenyl)prop-2-en-1-one
Also Known As: 2'-Chloro-4,4'-difluorochalcone, CHALCONE, 2'-CHLORO-4,4'-DIFLUORO-, 2-Propen-1-one, 1-(2-chloro-4-fluorophenyl)-3-(4-fluorophenyl)-, (E)-3-(2-chloro-4-fluoro-phenyl)-1-(4-fluorophenyl)prop-2-en-1-one, (E)-3-(2-chloro-4-fluorophenyl)-1-(4-fluorophenyl)prop-2-en-1-one
| Molecular Formula | C15H9ClF2O |
|---|---|
| Molecular Weight | 278.03 g/mol |
| LogP | 4.5143 |
| Topological Polar Surface Area | 17.07 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 3 |
| Exact Mass | 278.031 |
| Heavy Atoms | 19 |
| Complexity | 633.0939 |
Chemical Identifiers
| CAS Number | 7394-01-6 |
|---|---|
| SMILES | C1=CC(=CC=C1C(=O)/C=C/C2=C(C=C(C=C2)F)Cl)F |
Product Overview
2'-Chloro-4,4'-difluorochalcone (CAS 7394-01-6), with molecular formula C15H9ClF2O and molecular weight 278.03 g/mol. IUPAC: (E)-3-(2-chloro-4-fluorophenyl)-1-(4-fluorophenyl)prop-2-en-1-one.
Chemical Property Profile of 2'-Chloro-4,4'-difluorochalcone
Property Insights of 2'-Chloro-4,4'-difluorochalcone
The XLogP value of 4.5143 indicates that 2'-Chloro-4,4'-difluorochalcone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 17.07 Ų, 2'-Chloro-4,4'-difluorochalcone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2'-Chloro-4,4'-difluorochalcone has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2'-Chloro-4,4'-difluorochalcone?
The CAS number of 2'-Chloro-4,4'-difluorochalcone is 7394-01-6.
What is the molecular formula of 2'-Chloro-4,4'-difluorochalcone?
The molecular formula of 2'-Chloro-4,4'-difluorochalcone is C15H9ClF2O.
What is the molecular weight of 2'-Chloro-4,4'-difluorochalcone?
The molecular weight of 2'-Chloro-4,4'-difluorochalcone is 278.03 g/mol.
Where can I buy 2'-Chloro-4,4'-difluorochalcone?
You can request a quote for 2'-Chloro-4,4'-difluorochalcone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2'-Chloro-4,4'-difluorochalcone?
Yes, KEHONG BIO provides custom synthesis services for 2'-Chloro-4,4'-difluorochalcone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.