Naltrexazone
TL;DR: Naltrexazone (CAS 73674-86-9) is a chemical compound with molecular formula C20H25N3O3 and molecular weight 355.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4R,4aS,7Z,7aR,12bS)-3-(cyclopropylmethyl)-7-hydrazinylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
Also Known As: Naltrexazone, Naltrexone hydrazone, (4R,4aS,7E,7aR,12bS)-3-(cyclopropylmethyl)-7-hydrazinylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol, RefChem:927467
| Molecular Formula | C20H25N3O3 |
|---|---|
| Molecular Weight | 355.19 g/mol |
| LogP | 1.271 |
| Topological Polar Surface Area | 91.31 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 355.1896 |
| Heavy Atoms | 26 |
| Complexity | 835.83545 |
Chemical Identifiers
| CAS Number | 73674-86-9 |
|---|---|
| SMILES | C1CC1CN2CC[C@]34[C@@H]5/C(=N\N)/CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O |
Product Overview
Naltrexazone (CAS 73674-86-9), with molecular formula C20H25N3O3 and molecular weight 355.19 g/mol. IUPAC: (4R,4aS,7Z,7aR,12bS)-3-(cyclopropylmethyl)-7-hydrazinylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol.
Chemical Property Profile of Naltrexazone
Property Insights of Naltrexazone
The XLogP value of 1.271 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Naltrexazone. The TPSA of 91.31 Ų falls within the moderate polarity range, balancing permeability and solubility for Naltrexazone. Following Lipinski's Rule of Five, Naltrexazone has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Naltrexazone?
The CAS number of Naltrexazone is 73674-86-9.
What is the molecular formula of Naltrexazone?
The molecular formula of Naltrexazone is C20H25N3O3.
What is the molecular weight of Naltrexazone?
The molecular weight of Naltrexazone is 355.19 g/mol.
Where can I buy Naltrexazone?
You can request a quote for Naltrexazone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Naltrexazone?
Yes, KEHONG BIO provides custom synthesis services for Naltrexazone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.