Naloxazone
TL;DR: Naloxazone (CAS 73674-85-8) is a chemical compound with molecular formula C19H23N3O3 and molecular weight 341.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4R,4aS,7Z,7aR,12bS)-7-hydrazinylidene-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
Also Known As: naloxazone, Naloxone-6-hydrazone, (4R,4aS,7Z,7aR,12bS)-7-hydrazinylidene-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
| Molecular Formula | C19H23N3O3 |
|---|---|
| Molecular Weight | 341.17 g/mol |
| LogP | 1.047 |
| Topological Polar Surface Area | 91.31 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 341.17395 |
| Heavy Atoms | 25 |
| Complexity | 807.3492 |
Chemical Identifiers
| CAS Number | 73674-85-8 |
|---|---|
| SMILES | C=CCN1CC[C@]23[C@@H]4/C(=N\N)/CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O |
Product Overview
Naloxazone (CAS 73674-85-8), with molecular formula C19H23N3O3 and molecular weight 341.17 g/mol. IUPAC: (4R,4aS,7Z,7aR,12bS)-7-hydrazinylidene-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol.
Chemical Property Profile of Naloxazone
Property Insights of Naloxazone
The XLogP value of 1.047 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Naloxazone. The TPSA of 91.31 Ų falls within the moderate polarity range, balancing permeability and solubility for Naloxazone. Following Lipinski's Rule of Five, Naloxazone has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Naloxazone?
The CAS number of Naloxazone is 73674-85-8.
What is the molecular formula of Naloxazone?
The molecular formula of Naloxazone is C19H23N3O3.
What is the molecular weight of Naloxazone?
The molecular weight of Naloxazone is 341.17 g/mol.
Where can I buy Naloxazone?
You can request a quote for Naloxazone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Naloxazone?
Yes, KEHONG BIO provides custom synthesis services for Naloxazone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.