Bleomycin B6 structure

Bleomycin B6

TL;DR: Bleomycin B6 (CAS 73666-80-5) is a chemical compound with molecular formula C65H106N26O21S2 and molecular weight 1650.75 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(2S,3R,4R,5S,6S)-2-[(3R,4R,5R,6R)-2-[(1R,2R)-2-[[6-amino-2-[3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[(3R,4R)-5-[[(2R,3R)-1-[2-[4-[4-[4-[[N'-[4-[[N'-[4-(diaminomethylideneamino)butyl]carbamimidoyl]amino]butyl]carbamimidoyl]amino]butylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate

Also Known As: Bleomycin B6, N1-(20-Amino-6,13,20-triimino-5,7,12,14,19-pentaazaeicos-1-yl)bleomycinamide, Bleomycinamide, N1-(20-amino-6,13,20-triimino-5,7,12,14,19-pentaazaeicos-1-yl)-, n1-(20-amino-6,13,20-triimino-5,7,12,14,19-pentaazaeicos-1-yl)-bleomycinamide, [(2S,3R,4R,5S,6S)-2-[(3R,4R,5R,6R)-2-[(1R,2R)-2-[[6-amino-2-[3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[(3R,4R)-5-[[(2R,3R)-1-[2-[4-[4-[4-[[N'-[4-[[N'-[4-(diaminomethylideneamino)butyl]carbamimidoyl]amino]butyl]carbamimidoyl]amino]butylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate

CAS: 73666-80-5
Molecular Formula C65H106N26O21S2
Molecular Weight 1650.75 g/mol
LogP -9.54898
Topological Polar Surface Area 792.29 Ų
Hydrogen Bond Donors 26
Hydrogen Bond Acceptors 34
Rotatable Bonds 46
Exact Mass 1650.7467
Heavy Atoms 114
Complexity 3876.6863

Chemical Identifiers

CAS Number 73666-80-5
SMILES CC1=C(N=C(N=C1N)C(CC(=O)N)NC[C@@H](C(=O)N)N)C(=O)N[C@H]([C@H](C2=CN=CN2)OC3[C@@H]([C@@H]([C@H]([C@H](O3)CO)O)O)O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)CO)O)OC(=O)N)O)C(=O)NC(C)[C@@H]([C@@H](C)C(=O)N[C@H]([C@@H](C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCCCNC(=NCCCCNC(=NCCCCN=C(N)N)N)N)O

Product Overview

Bleomycin B6 (CAS 73666-80-5), with molecular formula C65H106N26O21S2 and molecular weight 1650.75 g/mol. IUPAC: [(2S,3R,4R,5S,6S)-2-[(3R,4R,5R,6R)-2-[(1R,2R)-2-[[6-amino-2-[3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[(3R,4R)-5-[[(2R,3R)-1-[2-[4-[4-[4-[[N'-[4-[[N'-[4-(diaminomethylideneamino)butyl]carbamimidoyl]amino]butyl]carbamimidoyl]amino]butylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Bleomycin B6

XLogP
-9.54898
TPSA (Topological Polar Surface Area)
792.29
Hydrogen Bond Donors
26
Hydrogen Bond Acceptors
34
Rotatable Bonds
46
Heavy Atoms
114
Complexity
3876.6863
Exact Mass
1650.7467
Monoisotopic Mass
1650.7467
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Bleomycin B6

The XLogP value of -9.54898 indicates that Bleomycin B6 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 792.29 Ų indicates high polarity, suggesting Bleomycin B6 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Bleomycin B6 has 26 hydrogen bond donor(s) and 34 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Bleomycin B6?

The CAS number of Bleomycin B6 is 73666-80-5.

What is the molecular formula of Bleomycin B6?

The molecular formula of Bleomycin B6 is C65H106N26O21S2.

What is the molecular weight of Bleomycin B6?

The molecular weight of Bleomycin B6 is 1650.75 g/mol.

Where can I buy Bleomycin B6?

You can request a quote for Bleomycin B6 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Bleomycin B6?

Yes, KEHONG BIO provides custom synthesis services for Bleomycin B6 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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