5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine
TL;DR: 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine (CAS 73630-11-2) is a chemical compound with molecular formula C10H17BrN2OSi and molecular weight 288.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5-bromopyrimidin-2-yl)oxy-tert-butyl-dimethylsilane
Also Known As: 5-Bromo-2-((tert-butyldimethylsilyl)oxy)pyrimidine, 5,5-Dibromo-Bapta, 2,3,4-Trifluoroanisole, 5-Bromo-2-(tert-butyldimethylsilyloxy)pyrimidine, 2-bromo-4-silyloxy pyrimidine
| Molecular Formula | C10H17BrN2OSi |
|---|---|
| Molecular Weight | 288.03 g/mol |
| LogP | 3.6231 |
| Topological Polar Surface Area | 35.01 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 288.02936 |
| Heavy Atoms | 15 |
| Complexity | 332.27078 |
Chemical Identifiers
| CAS Number | 73630-11-2 |
|---|---|
| SMILES | CC(C)(C)[Si](C)(C)OC1=NC=C(C=N1)Br |
Product Overview
5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine (CAS 73630-11-2), with molecular formula C10H17BrN2OSi and molecular weight 288.03 g/mol. IUPAC: (5-bromopyrimidin-2-yl)oxy-tert-butyl-dimethylsilane.
Chemical Property Profile of 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine
Property Insights of 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine
The XLogP value of 3.6231 indicates that 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.01 Ų, 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine?
The CAS number of 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine is 73630-11-2.
What is the molecular formula of 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine?
The molecular formula of 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine is C10H17BrN2OSi.
What is the molecular weight of 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine?
The molecular weight of 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine is 288.03 g/mol.
Where can I buy 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine?
You can request a quote for 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine?
Yes, KEHONG BIO provides custom synthesis services for 5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.