N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine
TL;DR: N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine (CAS 736169-67-8) is a chemical compound with molecular formula C12H12ClN3O and molecular weight 249.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine
Also Known As: N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine
| Molecular Formula | C12H12ClN3O |
|---|---|
| Molecular Weight | 249.07 g/mol |
| LogP | 3.19062 |
| Topological Polar Surface Area | 47.04 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 249.0669 |
| Heavy Atoms | 17 |
| Complexity | 516.65924 |
Chemical Identifiers
| CAS Number | 736169-67-8 |
|---|---|
| SMILES | CC1=CC(=C(C=C1Cl)OC)NC2=NC=CC=N2 |
Product Overview
N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine (CAS 736169-67-8), with molecular formula C12H12ClN3O and molecular weight 249.07 g/mol. IUPAC: N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine.
Chemical Property Profile of N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine
Property Insights of N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine
The XLogP value of 3.19062 indicates that N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.04 Ų, N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine?
The CAS number of N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine is 736169-67-8.
What is the molecular formula of N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine?
The molecular formula of N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine is C12H12ClN3O.
What is the molecular weight of N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine?
The molecular weight of N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine is 249.07 g/mol.
Where can I buy N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine?
You can request a quote for N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine?
Yes, KEHONG BIO provides custom synthesis services for N-(4-chloro-2-methoxy-5-methylphenyl)pyrimidin-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.