10-Hydroxyepi-21-O-methylkribine
TL;DR: 10-Hydroxyepi-21-O-methylkribine (CAS 73360-06-2) is a chemical compound with molecular formula C21H26N2O3 and molecular weight 354.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(12S,14R,16R,18R)-16-methoxy-11,18-dimethyl-17-oxa-1,11-diazapentacyclo[10.8.1.02,7.08,21.014,19]henicosa-2(7),3,5,8(21),19-pentaen-5-ol
Also Known As: 10-Hydroxyepi-21-O-methylkribine, 9H-10-Oxa-1,7b-diazabenzo(5,6)cyclohepta(1,2,3-jk)fluoren-5-ol,1,2,3,11,12,12a,13,13a-octahydro-11-methoxy-1,9-dimethyl-, (9R-(9alpha,11alpha,12abeta,13aalpha))-, 1,4:5,8-Dimethanonaphthalene, 1,2,3,4,5,8-hexahydro-, (1alpha,4alpha,5alpha,8alpha)-, (9R,11R,12aR,13aS)-11-Methoxy-1,9-dimethyl-1,2,3,11,12,12a,13,13a-octahydro-9H-10-oxa-1,7b-diazabenzo[5,6]cyclohepta[1,2,3-jk]fluoren-5-ol, 10-Methoxy-7,12-dimethyl-5,6,7,7a,8,8a,9,10-octahydro-12H-11-oxa-7,13a-diazabenzo[5,6]cyclohepta[1,2,3-jk]fluoren-3-ol
| Molecular Formula | C21H26N2O3 |
|---|---|
| Molecular Weight | 354.19 g/mol |
| LogP | 2.1 |
| Topological Polar Surface Area | 46.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 354.19434 |
| Heavy Atoms | 26 |
| Complexity | 582.0 |
Chemical Identifiers
| CAS Number | 73360-06-2 |
|---|---|
| SMILES | C[C@@H]1C2=CN3C4=C(C=C(C=C4)O)C5=C3[C@H](C[C@@H]2C[C@@H](O1)OC)N(CC5)C |
| InChIKey | DWIQQWDWFBHSLB-HBCXDPBJSA-N |
Product Overview
10-Hydroxyepi-21-O-methylkribine (CAS 73360-06-2), with molecular formula C21H26N2O3 and molecular weight 354.19 g/mol. IUPAC: (12S,14R,16R,18R)-16-methoxy-11,18-dimethyl-17-oxa-1,11-diazapentacyclo[10.8.1.02,7.08,21.014,19]henicosa-2(7),3,5,8(21),19-pentaen-5-ol.
Chemical Property Profile of 10-Hydroxyepi-21-O-methylkribine
Property Insights of 10-Hydroxyepi-21-O-methylkribine
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 10-Hydroxyepi-21-O-methylkribine. With a topological polar surface area (TPSA) of 46.9 Ų, 10-Hydroxyepi-21-O-methylkribine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 10-Hydroxyepi-21-O-methylkribine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10-Hydroxyepi-21-O-methylkribine?
The CAS number of 10-Hydroxyepi-21-O-methylkribine is 73360-06-2.
What is the molecular formula of 10-Hydroxyepi-21-O-methylkribine?
The molecular formula of 10-Hydroxyepi-21-O-methylkribine is C21H26N2O3.
What is the molecular weight of 10-Hydroxyepi-21-O-methylkribine?
The molecular weight of 10-Hydroxyepi-21-O-methylkribine is 354.19 g/mol.
Where can I buy 10-Hydroxyepi-21-O-methylkribine?
You can request a quote for 10-Hydroxyepi-21-O-methylkribine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10-Hydroxyepi-21-O-methylkribine?
Yes, KEHONG BIO provides custom synthesis services for 10-Hydroxyepi-21-O-methylkribine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.