Colchicine, N-deacetyl-N,N-dimethyl-
TL;DR: Colchicine, N-deacetyl-N,N-dimethyl- (CAS 7336-44-9) is a chemical compound with molecular formula C22H27NO5 and molecular weight 385.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(7S)-7-(dimethylamino)-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one
Also Known As: N-Methylcolchamine, N-Methyldemecolcine, Methylademecolcine, N-, Demecolcine, N-methyl-, N-Deacetyl-N,N-dimethylcolchicine
| Molecular Formula | C22H27NO5 |
|---|---|
| Molecular Weight | 385.19 g/mol |
| LogP | 1.8 |
| Topological Polar Surface Area | 57.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 385.18893 |
| Heavy Atoms | 28 |
| Complexity | 680.0 |
Chemical Identifiers
| CAS Number | 7336-44-9 |
|---|---|
| SMILES | CN(C)[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC |
| InChIKey | NDKXARFZWSQXGE-INIZCTEOSA-N |
Product Overview
Colchicine, N-deacetyl-N,N-dimethyl- (CAS 7336-44-9), with molecular formula C22H27NO5 and molecular weight 385.19 g/mol. IUPAC: (7S)-7-(dimethylamino)-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one.
Chemical Property Profile of Colchicine, N-deacetyl-N,N-dimethyl-
Property Insights of Colchicine, N-deacetyl-N,N-dimethyl-
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Colchicine, N-deacetyl-N,N-dimethyl-. With a topological polar surface area (TPSA) of 57.2 Ų, Colchicine, N-deacetyl-N,N-dimethyl- exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Colchicine, N-deacetyl-N,N-dimethyl- has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colchicine, N-deacetyl-N,N-dimethyl-?
The CAS number of Colchicine, N-deacetyl-N,N-dimethyl- is 7336-44-9.
What is the molecular formula of Colchicine, N-deacetyl-N,N-dimethyl-?
The molecular formula of Colchicine, N-deacetyl-N,N-dimethyl- is C22H27NO5.
What is the molecular weight of Colchicine, N-deacetyl-N,N-dimethyl-?
The molecular weight of Colchicine, N-deacetyl-N,N-dimethyl- is 385.19 g/mol.
Where can I buy Colchicine, N-deacetyl-N,N-dimethyl-?
You can request a quote for Colchicine, N-deacetyl-N,N-dimethyl- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colchicine, N-deacetyl-N,N-dimethyl-?
Yes, KEHONG BIO provides custom synthesis services for Colchicine, N-deacetyl-N,N-dimethyl- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.