N-Methylcolchicine
TL;DR: N-Methylcolchicine (CAS 7336-40-5) is a chemical compound with molecular formula C23H27NO6 and molecular weight 413.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-methyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Also Known As: N-Methylcolchicine, N-Acetylcolchamine, N-Acetylcolcemid, N-Acetyldemecolcine, COLCHICINE, N-METHYL-
| Molecular Formula | C23H27NO6 |
|---|---|
| Molecular Weight | 413.18 g/mol |
| LogP | 1.3 |
| Topological Polar Surface Area | 74.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 413.18384 |
| Heavy Atoms | 30 |
| Complexity | 770.0 |
Chemical Identifiers
| CAS Number | 7336-40-5 |
|---|---|
| SMILES | CC(=O)N(C)[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC |
| InChIKey | AHZFWPXTSZCLDJ-KRWDZBQOSA-N |
Product Overview
N-Methylcolchicine (CAS 7336-40-5), with molecular formula C23H27NO6 and molecular weight 413.18 g/mol. IUPAC: N-methyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.
Chemical Property Profile of N-Methylcolchicine
Property Insights of N-Methylcolchicine
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-Methylcolchicine. The TPSA of 74.3 Ų falls within the moderate polarity range, balancing permeability and solubility for N-Methylcolchicine. Following Lipinski's Rule of Five, N-Methylcolchicine has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-Methylcolchicine?
The CAS number of N-Methylcolchicine is 7336-40-5.
What is the molecular formula of N-Methylcolchicine?
The molecular formula of N-Methylcolchicine is C23H27NO6.
What is the molecular weight of N-Methylcolchicine?
The molecular weight of N-Methylcolchicine is 413.18 g/mol.
Where can I buy N-Methylcolchicine?
You can request a quote for N-Methylcolchicine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-Methylcolchicine?
Yes, KEHONG BIO provides custom synthesis services for N-Methylcolchicine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.