Macbecin II
TL;DR: Macbecin II (CAS 73341-73-8) is a chemical compound with molecular formula C30H44N2O8 and molecular weight 560.31 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(4E,6Z,8S,10E,12R,13S,14R,16S,17R)-20,22-dihydroxy-13,14,17-trimethoxy-4,8,10,12,16-pentamethyl-3-oxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18(22),19-hexaen-9-yl] carbamate
Also Known As: Macbecin II, C-14919 E-2, 2-Azabicyclo[16.3.1]docosane, geldanamycin deriv., [(4E,6Z,8S,10E,12R,13S,14R,16S,17R)-20,22-dihydroxy-13,14,17-trimethoxy-4,8,10,12,16-pentamethyl-3-oxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18(22),19-hexaen-9-yl] carbamate, Geldanamycin, 18,21-didehydro-6,17-didemethoxy-18,21-dideoxo-18,21-dihydroxy-15-methoxy-6-methyl-11-O-methyl-, (6S,15R)-
| Molecular Formula | C30H44N2O8 |
|---|---|
| Molecular Weight | 560.31 g/mol |
| LogP | 4.9785 |
| Topological Polar Surface Area | 149.57 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 4 |
| Exact Mass | 560.30975 |
| Heavy Atoms | 40 |
| Complexity | 1128.9507 |
Chemical Identifiers
| CAS Number | 73341-73-8 |
|---|---|
| SMILES | C[C@H]1C[C@H]([C@H]([C@@H](/C=C(/C([C@H](/C=C\C=C(\C(=O)NC2=CC(=CC(=C2O)[C@@H]1OC)O)/C)C)OC(=O)N)\C)C)OC)OC |
Product Overview
Macbecin II (CAS 73341-73-8), with molecular formula C30H44N2O8 and molecular weight 560.31 g/mol. IUPAC: [(4E,6Z,8S,10E,12R,13S,14R,16S,17R)-20,22-dihydroxy-13,14,17-trimethoxy-4,8,10,12,16-pentamethyl-3-oxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18(22),19-hexaen-9-yl] carbamate.
Chemical Property Profile of Macbecin II
Property Insights of Macbecin II
The XLogP value of 4.9785 indicates that Macbecin II is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 149.57 Ų indicates high polarity, suggesting Macbecin II may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Macbecin II has 4 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Macbecin II?
The CAS number of Macbecin II is 73341-73-8.
What is the molecular formula of Macbecin II?
The molecular formula of Macbecin II is C30H44N2O8.
What is the molecular weight of Macbecin II?
The molecular weight of Macbecin II is 560.31 g/mol.
Where can I buy Macbecin II?
You can request a quote for Macbecin II directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Macbecin II?
Yes, KEHONG BIO provides custom synthesis services for Macbecin II and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.