N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide
TL;DR: N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide (CAS 731007-08-2) is a chemical compound with molecular formula C14H12ClFN2O2S and molecular weight 326.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide
Also Known As: N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide, N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluoro-phenyl)acetamide
| Molecular Formula | C14H12ClFN2O2S |
|---|---|
| Molecular Weight | 326.03 g/mol |
| LogP | 3.62782 |
| Topological Polar Surface Area | 59.06 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 326.0292 |
| Heavy Atoms | 21 |
| Complexity | 694.74475 |
Chemical Identifiers
| CAS Number | 731007-08-2 |
|---|---|
| SMILES | CC1=C(SC(=N1)NC(=O)CC2=C(C=CC=C2Cl)F)C(=O)C |
Product Overview
N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide (CAS 731007-08-2), with molecular formula C14H12ClFN2O2S and molecular weight 326.03 g/mol. IUPAC: N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide.
Chemical Property Profile of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide
Property Insights of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide
The XLogP value of 3.62782 indicates that N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.06 Ų, N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide?
The CAS number of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide is 731007-08-2.
What is the molecular formula of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide?
The molecular formula of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide is C14H12ClFN2O2S.
What is the molecular weight of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide?
The molecular weight of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide is 326.03 g/mol.
Where can I buy N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide?
You can request a quote for N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide?
Yes, KEHONG BIO provides custom synthesis services for N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2-(2-chloro-6-fluorophenyl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.