Darodipine
TL;DR: Darodipine (CAS 72803-02-2) is a chemical compound with molecular formula C19H21N3O5 and molecular weight 371.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
diethyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Darodipino, Darodipinum, Dazodipin, Dazodipine, Plimo
| Molecular Formula | C19H21N3O5 |
|---|---|
| Molecular Weight | 371.15 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 104.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 7 |
| Exact Mass | 371.14813 |
| Heavy Atoms | 27 |
| Complexity | 632.0 |
Chemical Identifiers
| CAS Number | 72803-02-2 |
|---|---|
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC3=NON=C32)C(=O)OCC)C)C |
| InChIKey | QERUYFVNIOLCHV-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Darodipine (CAS 72803-02-2), with molecular formula C19H21N3O5 and molecular weight 371.15 g/mol. IUPAC: diethyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of Darodipine
Property Insights of Darodipine
The XLogP value of 4.2 indicates that Darodipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 104.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Darodipine. Following Lipinski's Rule of Five, Darodipine has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Darodipine?
The CAS number of Darodipine is 72803-02-2.
What is the molecular formula of Darodipine?
The molecular formula of Darodipine is C19H21N3O5.
What is the molecular weight of Darodipine?
The molecular weight of Darodipine is 371.15 g/mol.
Where can I buy Darodipine?
You can request a quote for Darodipine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Darodipine?
Yes, KEHONG BIO provides custom synthesis services for Darodipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.