AB01304433-01
TL;DR: AB01304433-01 (CAS 727683-73-0) is a chemical compound with molecular formula C20H15ClF4N4O2S and molecular weight 486.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-acetyl-3-amino-N-(4-chloro-2-fluorophenyl)-4-(trifluoromethyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide
Also Known As: AB01304433-01, AM-807/41629485, A3791/0160981, 6-acetyl-3-amino-N-(4-chloro-2-fluorophenyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide, 6-acetyl-3-amino-N-(4-chloro-2-fluorophenyl)-4-(trifluoromethyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide
| Molecular Formula | C20H15ClF4N4O2S |
|---|---|
| Molecular Weight | 486.05 g/mol |
| LogP | 4.8467 |
| Topological Polar Surface Area | 88.32 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 486.05405 |
| Heavy Atoms | 32 |
| Complexity | 1274.9438 |
Chemical Identifiers
| CAS Number | 727683-73-0 |
|---|---|
| SMILES | CC(=O)N1CCC2=C(C1)C(=C3C(=C(SC3=N2)C(=O)NC4=C(C=C(C=C4)Cl)F)N)C(F)(F)F |
Product Overview
AB01304433-01 (CAS 727683-73-0), with molecular formula C20H15ClF4N4O2S and molecular weight 486.05 g/mol. IUPAC: 6-acetyl-3-amino-N-(4-chloro-2-fluorophenyl)-4-(trifluoromethyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide.
Chemical Property Profile of AB01304433-01
Property Insights of AB01304433-01
The XLogP value of 4.8467 indicates that AB01304433-01 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.32 Ų falls within the moderate polarity range, balancing permeability and solubility for AB01304433-01. Following Lipinski's Rule of Five, AB01304433-01 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AB01304433-01?
The CAS number of AB01304433-01 is 727683-73-0.
What is the molecular formula of AB01304433-01?
The molecular formula of AB01304433-01 is C20H15ClF4N4O2S.
What is the molecular weight of AB01304433-01?
The molecular weight of AB01304433-01 is 486.05 g/mol.
Where can I buy AB01304433-01?
You can request a quote for AB01304433-01 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AB01304433-01?
Yes, KEHONG BIO provides custom synthesis services for AB01304433-01 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.