A3757/0159315 structure

A3757/0159315

TL;DR: A3757/0159315 (CAS 727674-00-2) is a chemical compound with molecular formula C18H17N5OS and molecular weight 351.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

7,14,14-trimethyl-4-pyridin-3-yl-13-oxa-10-thia-3,5,6,8-tetrazatetracyclo[7.7.0.02,6.011,16]hexadeca-1(9),2,4,7,11(16)-pentaene

Also Known As: A3757/0159315, 5,10,10-trimethyl-2-(pyridin-3-yl)-10,11-dihydro-8H-pyrano[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine, 5,10,10-TRIMETHYL-2-(3-PYRIDYL)-10,11-DIHYDRO-8H-PYRANO[4',3':4,5]THIENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE, 8H-Pyrano[4',3':4,5]thieno[3,2-E][1,2,4]triazolo[1,5-c]pyrimidine, 10,11-dihydro-5,10,10-trimethyl-2-(3-pyridinyl)-

CAS: 727674-00-2
Molecular Formula C18H17N5OS
Molecular Weight 351.12 g/mol
LogP 3.56072
Topological Polar Surface Area 65.2 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 6
Rotatable Bonds 1
Exact Mass 351.1154
Heavy Atoms 25
Complexity 1113.1094

Chemical Identifiers

CAS Number 727674-00-2
SMILES CC1=NC2=C(C3=C(S2)COC(C3)(C)C)C4=NC(=NN14)C5=CN=CC=C5

Product Overview

A3757/0159315 (CAS 727674-00-2), with molecular formula C18H17N5OS and molecular weight 351.12 g/mol. IUPAC: 7,14,14-trimethyl-4-pyridin-3-yl-13-oxa-10-thia-3,5,6,8-tetrazatetracyclo[7.7.0.02,6.011,16]hexadeca-1(9),2,4,7,11(16)-pentaene.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of A3757/0159315

XLogP
3.56072
TPSA (Topological Polar Surface Area)
65.2
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
6
Rotatable Bonds
1
Heavy Atoms
25
Complexity
1113.1094
Exact Mass
351.1154
Monoisotopic Mass
351.1154
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of A3757/0159315

The XLogP value of 3.56072 indicates that A3757/0159315 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.2 Ų falls within the moderate polarity range, balancing permeability and solubility for A3757/0159315. Following Lipinski's Rule of Five, A3757/0159315 has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of A3757/0159315?

The CAS number of A3757/0159315 is 727674-00-2.

What is the molecular formula of A3757/0159315?

The molecular formula of A3757/0159315 is C18H17N5OS.

What is the molecular weight of A3757/0159315?

The molecular weight of A3757/0159315 is 351.12 g/mol.

Where can I buy A3757/0159315?

You can request a quote for A3757/0159315 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for A3757/0159315?

Yes, KEHONG BIO provides custom synthesis services for A3757/0159315 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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