A3730/0158123
TL;DR: A3730/0158123 (CAS 727663-24-3) is a chemical compound with molecular formula C22H20F4N4O2S and molecular weight 480.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-acetyl-3-amino-N-[2-(4-fluorophenyl)ethyl]-4-(trifluoromethyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide
Also Known As: A3730/0158123, 6-acetyl-3-amino-N-[2-(4-fluorophenyl)ethyl]-4-(trifluoromethyl)-5H,6H,7H,8H-thieno[2,3-b]1,6-naphthyridine-2-carboxamide, 6-acetyl-3-amino-N-(4-fluorophenethyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide, 6-acetyl-3-amino-N-[2-(4-fluorophenyl)ethyl]-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide, 6-acetyl-3-amino-N-[2-(4-fluorophenyl)ethyl]-4-(trifluoromethyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide
| Molecular Formula | C22H20F4N4O2S |
|---|---|
| Molecular Weight | 480.12 g/mol |
| LogP | 3.9135 |
| Topological Polar Surface Area | 88.32 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 480.1243 |
| Heavy Atoms | 33 |
| Complexity | 1238.1522 |
Chemical Identifiers
| CAS Number | 727663-24-3 |
|---|---|
| SMILES | CC(=O)N1CCC2=C(C1)C(=C3C(=C(SC3=N2)C(=O)NCCC4=CC=C(C=C4)F)N)C(F)(F)F |
Product Overview
A3730/0158123 (CAS 727663-24-3), with molecular formula C22H20F4N4O2S and molecular weight 480.12 g/mol. IUPAC: 6-acetyl-3-amino-N-[2-(4-fluorophenyl)ethyl]-4-(trifluoromethyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide.
Chemical Property Profile of A3730/0158123
Property Insights of A3730/0158123
The XLogP value of 3.9135 indicates that A3730/0158123 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.32 Ų falls within the moderate polarity range, balancing permeability and solubility for A3730/0158123. Following Lipinski's Rule of Five, A3730/0158123 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of A3730/0158123?
The CAS number of A3730/0158123 is 727663-24-3.
What is the molecular formula of A3730/0158123?
The molecular formula of A3730/0158123 is C22H20F4N4O2S.
What is the molecular weight of A3730/0158123?
The molecular weight of A3730/0158123 is 480.12 g/mol.
Where can I buy A3730/0158123?
You can request a quote for A3730/0158123 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for A3730/0158123?
Yes, KEHONG BIO provides custom synthesis services for A3730/0158123 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.