2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine
TL;DR: 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine (CAS 727422-01-7) is a chemical compound with molecular formula C11H9ClFN3O and molecular weight 253.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine
Also Known As: 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine, (2-chloro-5-fluoropyrimidin-4-yl)(2-methoxyphenyl)amine, 2-Chloro-5-fluoro-n-(2-methoxyphenyl)-4-pyrimidinamine, 4-Pyrimidinamine, 2-chloro-5-fluoro-N-(2-methoxyphenyl)-, A3726/0157905
| Molecular Formula | C11H9ClFN3O |
|---|---|
| Molecular Weight | 253.04 g/mol |
| LogP | 3.0213 |
| Topological Polar Surface Area | 47.04 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 253.04182 |
| Heavy Atoms | 17 |
| Complexity | 535.87506 |
Chemical Identifiers
| CAS Number | 727422-01-7 |
|---|---|
| SMILES | COC1=CC=CC=C1NC2=NC(=NC=C2F)Cl |
Product Overview
2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine (CAS 727422-01-7), with molecular formula C11H9ClFN3O and molecular weight 253.04 g/mol. IUPAC: 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine.
Chemical Property Profile of 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine
Property Insights of 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine
The XLogP value of 3.0213 indicates that 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.04 Ų, 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine?
The CAS number of 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine is 727422-01-7.
What is the molecular formula of 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine?
The molecular formula of 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine is C11H9ClFN3O.
What is the molecular weight of 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine?
The molecular weight of 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine is 253.04 g/mol.
Where can I buy 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine?
You can request a quote for 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine?
Yes, KEHONG BIO provides custom synthesis services for 2-chloro-5-fluoro-N-(2-methoxyphenyl)pyrimidin-4-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.