![6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one structure](/static/products/727/727394-94-7.png)
6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one
TL;DR: 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one (CAS 727394-94-7) is a chemical compound with molecular formula C27H24N4O3 and molecular weight 452.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(2,4-dimethoxyphenyl)-9-naphthalen-1-yl-5,6,7,9-tetrahydro-4H-[1,2,4]triazolo[5,1-b]quinazolin-8-one
Also Known As: 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one, 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro[1,2,4]triazolo[5,1-b]quinazolin-8-ol, 6-(2,4-dimethoxyphenyl)-9-naphthalen-1-yl-5,6,7,9-tetrahydro-1H-[1,2,4]triazolo[5,1-b]quinazolin-8-one
| Molecular Formula | C27H24N4O3 |
|---|---|
| Molecular Weight | 452.18 g/mol |
| LogP | 4.8642 |
| Topological Polar Surface Area | 78.27 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 452.18484 |
| Heavy Atoms | 34 |
| Complexity | 1450.0498 |
Chemical Identifiers
| CAS Number | 727394-94-7 |
|---|---|
| SMILES | COC1=CC(=C(C=C1)C2CC3=C(C(N4C(=NC=N4)N3)C5=CC=CC6=CC=CC=C65)C(=O)C2)OC |
Product Overview
6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one (CAS 727394-94-7), with molecular formula C27H24N4O3 and molecular weight 452.18 g/mol. IUPAC: 6-(2,4-dimethoxyphenyl)-9-naphthalen-1-yl-5,6,7,9-tetrahydro-4H-[1,2,4]triazolo[5,1-b]quinazolin-8-one.
Chemical Property Profile of 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one
Property Insights of 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one
The XLogP value of 4.8642 indicates that 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 78.27 Ų falls within the moderate polarity range, balancing permeability and solubility for 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one. Following Lipinski's Rule of Five, 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one?
The CAS number of 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one is 727394-94-7.
What is the molecular formula of 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one?
The molecular formula of 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one is C27H24N4O3.
What is the molecular weight of 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one?
The molecular weight of 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one is 452.18 g/mol.
Where can I buy 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one?
You can request a quote for 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one?
Yes, KEHONG BIO provides custom synthesis services for 6-(2,4-dimethoxyphenyl)-9-(naphthalen-1-yl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.