![12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol structure](/static/products/727/727393-73-9.png)
12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol
TL;DR: 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol (CAS 727393-73-9) is a chemical compound with molecular formula C26H23N3O3S and molecular weight 457.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
12-(3,4-dimethoxyphenyl)-3-thiophen-2-yl-3,4,5,12-tetrahydro-2H-benzimidazolo[2,1-b]quinazolin-1-one
Also Known As: 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol, 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-3,4,5,12-tetrahydrobenzo[4,5]imidazo[2,1-b]quinazolin-1(2H)-one, 12-(3,4-dimethoxyphenyl)-3-thiophen-2-yl-3,4,5,12-tetrahydro-2H-benzimidazolo[2,1-b]quinazolin-1-one
| Molecular Formula | C26H23N3O3S |
|---|---|
| Molecular Weight | 457.15 g/mol |
| LogP | 5.5307 |
| Topological Polar Surface Area | 65.38 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 457.14603 |
| Heavy Atoms | 33 |
| Complexity | 1403.6885 |
Chemical Identifiers
| CAS Number | 727393-73-9 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)C2C3=C(CC(CC3=O)C4=CC=CS4)NC5=NC6=CC=CC=C6N25)OC |
Product Overview
12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol (CAS 727393-73-9), with molecular formula C26H23N3O3S and molecular weight 457.15 g/mol. IUPAC: 12-(3,4-dimethoxyphenyl)-3-thiophen-2-yl-3,4,5,12-tetrahydro-2H-benzimidazolo[2,1-b]quinazolin-1-one.
Chemical Property Profile of 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol
Property Insights of 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol
The XLogP value of 5.5307 indicates that 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.38 Ų falls within the moderate polarity range, balancing permeability and solubility for 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol. Following Lipinski's Rule of Five, 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol?
The CAS number of 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol is 727393-73-9.
What is the molecular formula of 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol?
The molecular formula of 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol is C26H23N3O3S.
What is the molecular weight of 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol?
The molecular weight of 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol is 457.15 g/mol.
Where can I buy 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol?
You can request a quote for 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol?
Yes, KEHONG BIO provides custom synthesis services for 12-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-2,3,4,12-tetrahydrobenzimidazo[2,1-b]quinazolin-1-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.