![1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone structure](/static/products/7273/727392-18-9.webp)
1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone
TL;DR: 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone (CAS 727392-18-9) is a chemical compound with molecular formula C22H23F3N4O and molecular weight 416.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(3-phenyl-3,4-dihydropyrazol-2-yl)-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone
Also Known As: 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone, 1-(5-phenyl(2-pyrazolinyl))-2-{4-[3-(trifluoromethyl)phenyl]piperazinyl}ethan- 1-one, 1-(3-phenyl-3,4-dihydropyrazol-2-yl)-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone, 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethanone, 1-(5-PHENYL-4,5-DIHYDRO-1H-PYRAZOL-1-YL)-2-{4-[3-(TRIFLUOROMETHYL)PHENYL]PIPERAZIN-1-YL}ETHAN-1-ONE
| Molecular Formula | C22H23F3N4O |
|---|---|
| Molecular Weight | 416.18 g/mol |
| LogP | 3.7868 |
| Topological Polar Surface Area | 39.15 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 416.1824 |
| Heavy Atoms | 30 |
| Complexity | 908.0987 |
Chemical Identifiers
| CAS Number | 727392-18-9 |
|---|---|
| SMILES | C1CN(CCN1CC(=O)N2C(CC=N2)C3=CC=CC=C3)C4=CC=CC(=C4)C(F)(F)F |
Product Overview
1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone (CAS 727392-18-9), with molecular formula C22H23F3N4O and molecular weight 416.18 g/mol. IUPAC: 1-(3-phenyl-3,4-dihydropyrazol-2-yl)-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone.
Chemical Property Profile of 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone
Property Insights of 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone
The XLogP value of 3.7868 indicates that 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 39.15 Ų, 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone?
The CAS number of 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone is 727392-18-9.
What is the molecular formula of 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone?
The molecular formula of 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone is C22H23F3N4O.
What is the molecular weight of 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone?
The molecular weight of 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone is 416.18 g/mol.
Where can I buy 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone?
You can request a quote for 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone?
Yes, KEHONG BIO provides custom synthesis services for 1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.