Comfrey structure

Comfrey

TL;DR: Comfrey (CAS 72698-57-8) is a chemical compound with molecular formula C20H31NO7 and molecular weight 397.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[7-[(E)-2-methylbut-2-enoyl]oxy-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl]methyl 2-hydroxy-2-(1-hydroxyethyl)-3-methylbutanoate

Also Known As: comfrey, Symphytine oxide, [7-[(E)-2-methylbut-2-enoyl]oxy-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl]methyl 2-hydroxy-2-(1-hydroxyethyl)-3-methylbutanoate, 2-Butenoic acid, 2-methyl-, 7-((2,3-dihydroxy-2-(1-methylethyl)-1-oxobutoxy)methyl)-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl ester, N-oxide, (1R-(1alpha(E),7(2S*,3S*),7abeta))-

CAS: 72698-57-8
Molecular Formula C20H31NO7
Molecular Weight 397.21 g/mol
LogP 1.2024
Topological Polar Surface Area 116.12 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 7
Rotatable Bonds 7
Exact Mass 397.21005
Heavy Atoms 28
Complexity 674.0417

Chemical Identifiers

CAS Number 72698-57-8
SMILES C/C=C(\C)/C(=O)OC1CC[N+]2(C1C(=CC2)COC(=O)C(C(C)C)(C(C)O)O)[O-]

Product Overview

Comfrey (CAS 72698-57-8), with molecular formula C20H31NO7 and molecular weight 397.21 g/mol. IUPAC: [7-[(E)-2-methylbut-2-enoyl]oxy-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl]methyl 2-hydroxy-2-(1-hydroxyethyl)-3-methylbutanoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Comfrey

XLogP
1.2024
TPSA (Topological Polar Surface Area)
116.12
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
7
Rotatable Bonds
7
Heavy Atoms
28
Complexity
674.0417
Exact Mass
397.21005
Monoisotopic Mass
397.21005
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Comfrey

The XLogP value of 1.2024 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Comfrey. The TPSA of 116.12 Ų falls within the moderate polarity range, balancing permeability and solubility for Comfrey. Following Lipinski's Rule of Five, Comfrey has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Comfrey?

The CAS number of Comfrey is 72698-57-8.

What is the molecular formula of Comfrey?

The molecular formula of Comfrey is C20H31NO7.

What is the molecular weight of Comfrey?

The molecular weight of Comfrey is 397.21 g/mol.

Where can I buy Comfrey?

You can request a quote for Comfrey directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Comfrey?

Yes, KEHONG BIO provides custom synthesis services for Comfrey and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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