ICR-371 Free base
TL;DR: ICR-371 Free base (CAS 72667-35-7) is a chemical compound with molecular formula C21H26Cl2N4O and molecular weight 420.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N'-(2-butoxy-7-chlorobenzo[b][1,5]naphthyridin-10-yl)-N-(2-chloroethyl)propane-1,3-diamine
Also Known As: ICR-371 Free base, NIOSH/TX7033800, ICR 371, N-(2-Butoxy-7-chlorobenzo(b)-1,5-naphthyridin-10-yl)-N'-(2-chloroethyl)-1,3-propanediamine, 1,3-Propanediamine, N-(2-butoxy-7-chlorobenzo(b)-1,5-naphthyridin-10-yl)-N'-(2-chloroethyl)-
| Molecular Formula | C21H26Cl2N4O |
|---|---|
| Molecular Weight | 420.15 g/mol |
| LogP | 5.8 |
| Topological Polar Surface Area | 59.1 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 11 |
| Exact Mass | 420.14838 |
| Heavy Atoms | 28 |
| Complexity | 445.0 |
Chemical Identifiers
| CAS Number | 72667-35-7 |
|---|---|
| SMILES | CCCCOC1=NC2=C(C3=C(C=C(C=C3)Cl)N=C2C=C1)NCCCNCCCl |
| InChIKey | JOJKDEYBURDPEB-UHFFFAOYSA-N |
Product Overview
ICR-371 Free base (CAS 72667-35-7), with molecular formula C21H26Cl2N4O and molecular weight 420.15 g/mol. IUPAC: N'-(2-butoxy-7-chlorobenzo[b][1,5]naphthyridin-10-yl)-N-(2-chloroethyl)propane-1,3-diamine.
Chemical Property Profile of ICR-371 Free base
Property Insights of ICR-371 Free base
The XLogP value of 5.8 indicates that ICR-371 Free base is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.1 Ų, ICR-371 Free base exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, ICR-371 Free base has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of ICR-371 Free base?
The CAS number of ICR-371 Free base is 72667-35-7.
What is the molecular formula of ICR-371 Free base?
The molecular formula of ICR-371 Free base is C21H26Cl2N4O.
What is the molecular weight of ICR-371 Free base?
The molecular weight of ICR-371 Free base is 420.15 g/mol.
Where can I buy ICR-371 Free base?
You can request a quote for ICR-371 Free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for ICR-371 Free base?
Yes, KEHONG BIO provides custom synthesis services for ICR-371 Free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.