4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide
TL;DR: 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide (CAS 72632-83-8) is a chemical compound with molecular formula C10H8N4O3S and molecular weight 264.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide
Also Known As: 4-amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide, RefChem:289978
| Molecular Formula | C10H8N4O3S |
|---|---|
| Molecular Weight | 264.03 g/mol |
| LogP | 1.6 |
| Topological Polar Surface Area | 156.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 264.0317 |
| Heavy Atoms | 18 |
| Complexity | 341.0 |
Chemical Identifiers
| CAS Number | 72632-83-8 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=C(C(=NS2)C(=O)N)N)[N+](=O)[O-] |
| InChIKey | KDDAOCSYJUVIHH-UHFFFAOYSA-N |
Product Overview
4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide (CAS 72632-83-8), with molecular formula C10H8N4O3S and molecular weight 264.03 g/mol. IUPAC: 4-amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide.
Chemical Property Profile of 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide
Property Insights of 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide. The TPSA of 156.0 Ų indicates high polarity, suggesting 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide?
The CAS number of 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide is 72632-83-8.
What is the molecular formula of 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide?
The molecular formula of 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide is C10H8N4O3S.
What is the molecular weight of 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide?
The molecular weight of 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide is 264.03 g/mol.
Where can I buy 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide?
You can request a quote for 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.