Hydrocortisone buteprate
TL;DR: Hydrocortisone buteprate (CAS 72590-77-3) is a chemical compound with molecular formula C28H40O7 and molecular weight 488.28 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-10,13-dimethyl-3-oxo-17-(2-propanoyloxyacetyl)-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] butanoate
Also Known As: Hydrocortisone buteprate, Hydrocortisone probutate, Pandel, Datenin, Hayulon
| Molecular Formula | C28H40O7 |
|---|---|
| Molecular Weight | 488.28 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 107.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 9 |
| Exact Mass | 488.2774 |
| Heavy Atoms | 35 |
| Complexity | 938.0 |
Chemical Identifiers
| CAS Number | 72590-77-3 |
|---|---|
| SMILES | CCCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)C(=O)COC(=O)CC |
| InChIKey | FOGXJPFPZOHSQS-AYVLZSQQSA-N |
Patent-Derived Application Labels
Derived from 9 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Hydrocortisone buteprate (CAS 72590-77-3), with molecular formula C28H40O7 and molecular weight 488.28 g/mol. IUPAC: [(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-10,13-dimethyl-3-oxo-17-(2-propanoyloxyacetyl)-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] butanoate.
Chemical Property Profile of Hydrocortisone buteprate
Property Insights of Hydrocortisone buteprate
The XLogP value of 4.2 indicates that Hydrocortisone buteprate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 107.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Hydrocortisone buteprate. Following Lipinski's Rule of Five, Hydrocortisone buteprate has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Hydrocortisone buteprate?
The CAS number of Hydrocortisone buteprate is 72590-77-3.
What is the molecular formula of Hydrocortisone buteprate?
The molecular formula of Hydrocortisone buteprate is C28H40O7.
What is the molecular weight of Hydrocortisone buteprate?
The molecular weight of Hydrocortisone buteprate is 488.28 g/mol.
Where can I buy Hydrocortisone buteprate?
You can request a quote for Hydrocortisone buteprate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Hydrocortisone buteprate?
Yes, KEHONG BIO provides custom synthesis services for Hydrocortisone buteprate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.