Piclonidine structure

Piclonidine

TL;DR: Piclonidine (CAS 72467-44-8) is a chemical compound with molecular formula C14H17Cl2N3O and molecular weight 313.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-(2,6-dichlorophenyl)-N-(oxan-2-yl)-4,5-dihydro-1H-imidazol-2-amine

Also Known As: Piclonidine, Piclonidina, Piclonidinum, Piclonidine [INN], Piclonidinum [INN-Latin]

CAS: 72467-44-8
Molecular Formula C14H17Cl2N3O
Molecular Weight 313.07 g/mol
LogP 2.9
Topological Polar Surface Area 36.9 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 3
Exact Mass 313.07486
Heavy Atoms 20
Complexity 356.0

Chemical Identifiers

CAS Number 72467-44-8
SMILES C1CCOC(C1)N(C2=C(C=CC=C2Cl)Cl)C3=NCCN3
InChIKey NYQGJEQCYOJBPV-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (29 patents)

Product Overview

Piclonidine (CAS 72467-44-8), with molecular formula C14H17Cl2N3O and molecular weight 313.07 g/mol. IUPAC: N-(2,6-dichlorophenyl)-N-(oxan-2-yl)-4,5-dihydro-1H-imidazol-2-amine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Piclonidine

XLogP
2.9
TPSA (Topological Polar Surface Area)
36.9
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
3
Heavy Atoms
20
Complexity
356.0
Exact Mass
313.07486
Monoisotopic Mass
313.07486
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Piclonidine

The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Piclonidine. With a topological polar surface area (TPSA) of 36.9 Ų, Piclonidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Piclonidine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Piclonidine?

The CAS number of Piclonidine is 72467-44-8.

What is the molecular formula of Piclonidine?

The molecular formula of Piclonidine is C14H17Cl2N3O.

What is the molecular weight of Piclonidine?

The molecular weight of Piclonidine is 313.07 g/mol.

Where can I buy Piclonidine?

You can request a quote for Piclonidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Piclonidine?

Yes, KEHONG BIO provides custom synthesis services for Piclonidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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