2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide
TL;DR: 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide (CAS 724431-41-8) is a chemical compound with molecular formula C12H6Cl2FIN2O and molecular weight 409.89 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,6-dichloro-5-fluoro-N-(4-iodophenyl)pyridine-3-carboxamide
Also Known As: 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide, AP-501/42583430, 2,6-dichloro-5-fluoro-N-(4-iodophenyl)pyridine-3-carboxamide
| Molecular Formula | C12H6Cl2FIN2O |
|---|---|
| Molecular Weight | 409.89 g/mol |
| LogP | 4.3844 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 409.88858 |
| Heavy Atoms | 19 |
| Complexity | 634.37164 |
Chemical Identifiers
| CAS Number | 724431-41-8 |
|---|---|
| SMILES | C1=CC(=CC=C1NC(=O)C2=CC(=C(N=C2Cl)Cl)F)I |
Product Overview
2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide (CAS 724431-41-8), with molecular formula C12H6Cl2FIN2O and molecular weight 409.89 g/mol. IUPAC: 2,6-dichloro-5-fluoro-N-(4-iodophenyl)pyridine-3-carboxamide.
Chemical Property Profile of 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide
Property Insights of 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide
The XLogP value of 4.3844 indicates that 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide?
The CAS number of 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide is 724431-41-8.
What is the molecular formula of 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide?
The molecular formula of 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide is C12H6Cl2FIN2O.
What is the molecular weight of 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide?
The molecular weight of 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide is 409.89 g/mol.
Where can I buy 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide?
You can request a quote for 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for 2,6-dichloro-5-fluoro-N-(4-iodophenyl)nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.