N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide
TL;DR: N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide (CAS 724430-02-8) is a chemical compound with molecular formula C14H9Cl2FN2O2 and molecular weight 326.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3-acetylphenyl)-2,6-dichloro-5-fluoropyridine-3-carboxamide
Also Known As: N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide, AP-501/42302413, N-(3-acetylphenyl)-2,6-dichloro-5-fluoropyridine-3-carboxamide
| Molecular Formula | C14H9Cl2FN2O2 |
|---|---|
| Molecular Weight | 326.00 g/mol |
| LogP | 3.9824 |
| Topological Polar Surface Area | 59.06 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 326.0025 |
| Heavy Atoms | 21 |
| Complexity | 734.9091 |
Chemical Identifiers
| CAS Number | 724430-02-8 |
|---|---|
| SMILES | CC(=O)C1=CC(=CC=C1)NC(=O)C2=CC(=C(N=C2Cl)Cl)F |
Product Overview
N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide (CAS 724430-02-8), with molecular formula C14H9Cl2FN2O2 and molecular weight 326.00 g/mol. IUPAC: N-(3-acetylphenyl)-2,6-dichloro-5-fluoropyridine-3-carboxamide.
Chemical Property Profile of N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide
Property Insights of N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide
The XLogP value of 3.9824 indicates that N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.06 Ų, N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide?
The CAS number of N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide is 724430-02-8.
What is the molecular formula of N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide?
The molecular formula of N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide is C14H9Cl2FN2O2.
What is the molecular weight of N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide?
The molecular weight of N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide is 326.00 g/mol.
Where can I buy N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide?
You can request a quote for N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide?
Yes, KEHONG BIO provides custom synthesis services for N-(3-acetylphenyl)-2,6-dichloro-5-fluoronicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.