2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide
TL;DR: 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide (CAS 724429-95-2) is a chemical compound with molecular formula C14H11Cl2FN2O and molecular weight 312.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoropyridine-3-carboxamide
Also Known As: AP-501/42302406, 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide, 2,6-Dichloro-N-(2,6-dimethylphenyl)-5-fluoro-3-pyridinecarboxamide, 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoropyridine-3-carboxamide
| Molecular Formula | C14H11Cl2FN2O |
|---|---|
| Molecular Weight | 312.02 g/mol |
| LogP | 4.39664 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 312.02325 |
| Heavy Atoms | 20 |
| Complexity | 668.8644 |
Chemical Identifiers
| CAS Number | 724429-95-2 |
|---|---|
| SMILES | CC1=C(C(=CC=C1)C)NC(=O)C2=CC(=C(N=C2Cl)Cl)F |
Product Overview
2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide (CAS 724429-95-2), with molecular formula C14H11Cl2FN2O and molecular weight 312.02 g/mol. IUPAC: 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoropyridine-3-carboxamide.
Chemical Property Profile of 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide
Property Insights of 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide
The XLogP value of 4.39664 indicates that 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide?
The CAS number of 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide is 724429-95-2.
What is the molecular formula of 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide?
The molecular formula of 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide is C14H11Cl2FN2O.
What is the molecular weight of 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide?
The molecular weight of 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide is 312.02 g/mol.
Where can I buy 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide?
You can request a quote for 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide?
Yes, KEHONG BIO provides custom synthesis services for 2,6-dichloro-N-(2,6-dimethylphenyl)-5-fluoronicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.