((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione
TL;DR: ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione (CAS 7243-18-7) is a chemical compound with molecular formula C18H16F6N4S and molecular weight 434.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[3,5-bis(trifluoromethyl)phenyl]-4-pyridin-2-ylpiperazine-1-carbothioamide
Also Known As: ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione, N-[3,5-bis(trifluoromethyl)phenyl]-4-pyridin-2-ylpiperazine-1-carbothioamide, N-[3,5-bis(trifluoromethyl)phenyl]-4-(pyridin-2-yl)piperazine-1-carbothioamide, N-(3,5-Bis(trifluoromethyl)phenyl)-4-(pyridin-2-yl)piperazine-1-carbothioamide, N-[3,5-bis(trifluoromethyl)phenyl]-4-(2-pyridyl)piperazine-1-carbothioamide
| Molecular Formula | C18H16F6N4S |
|---|---|
| Molecular Weight | 434.10 g/mol |
| LogP | 4.6382 |
| Topological Polar Surface Area | 31.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 434.09998 |
| Heavy Atoms | 29 |
| Complexity | 828.64044 |
Chemical Identifiers
| CAS Number | 7243-18-7 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC=N2)C(=S)NC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F |
Product Overview
((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione (CAS 7243-18-7), with molecular formula C18H16F6N4S and molecular weight 434.10 g/mol. IUPAC: N-[3,5-bis(trifluoromethyl)phenyl]-4-pyridin-2-ylpiperazine-1-carbothioamide.
Chemical Property Profile of ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione
Property Insights of ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione
The XLogP value of 4.6382 indicates that ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 31.4 Ų, ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione?
The CAS number of ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione is 7243-18-7.
What is the molecular formula of ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione?
The molecular formula of ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione is C18H16F6N4S.
What is the molecular weight of ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione?
The molecular weight of ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione is 434.10 g/mol.
Where can I buy ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione?
You can request a quote for ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione?
Yes, KEHONG BIO provides custom synthesis services for ((3,5-bis(trifluoromethyl)phenyl)amino)(4-(2-pyridyl)piperazinyl)methane-1-thione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.