N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin structure

N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin

TL;DR: N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin (CAS 72402-71-2) is a chemical compound with molecular formula C36H31F3N2O14 and molecular weight 772.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[6-[(3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl)oxy]-2-methyl-4-[(2,2,2-trifluoroacetyl)amino]oxan-3-yl] 4-nitrobenzoate

Also Known As: N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin, N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin, [(2S,3S,4S,6R)-6-[[(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-2-methyl-4-[(2,2,2-trifluoroacetyl)amino]oxan-3-yl] 4-nitrobenzoate, [6-[(3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl)oxy]-2-methyl-4-[(2,2,2-trifluoroacetyl)amino]oxan-3-yl] 4-nitrobenzoate, 3-Acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-4-O-(4-nitrobenzoyl)-3-[(2,2,2-trifluoro-1-hydroxyethylidene)amino]hexopyranoside

CAS: 72402-71-2
Molecular Formula C36H31F3N2O14
Molecular Weight 772.17 g/mol
LogP 5.3
Topological Polar Surface Area 241.0 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 17
Rotatable Bonds 8
Exact Mass 772.1727
Heavy Atoms 55
Complexity 1530.0

Chemical Identifiers

CAS Number 72402-71-2
SMILES CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)C)O)NC(=O)C(F)(F)F)OC(=O)C6=CC=C(C=C6)[N+](=O)[O-]
InChIKey HGBZBLPEFVMINN-UHFFFAOYSA-N

Product Overview

N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin (CAS 72402-71-2), with molecular formula C36H31F3N2O14 and molecular weight 772.17 g/mol. IUPAC: [6-[(3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl)oxy]-2-methyl-4-[(2,2,2-trifluoroacetyl)amino]oxan-3-yl] 4-nitrobenzoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin

XLogP
5.3
TPSA (Topological Polar Surface Area)
241.0
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
17
Rotatable Bonds
8
Heavy Atoms
55
Complexity
1530.0
Exact Mass
772.1727
Monoisotopic Mass
772.1727
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin

The XLogP value of 5.3 indicates that N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 241.0 Ų indicates high polarity, suggesting N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin has 4 hydrogen bond donor(s) and 17 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin?

The CAS number of N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin is 72402-71-2.

What is the molecular formula of N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin?

The molecular formula of N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin is C36H31F3N2O14.

What is the molecular weight of N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin?

The molecular weight of N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin is 772.17 g/mol.

Where can I buy N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin?

You can request a quote for N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin?

Yes, KEHONG BIO provides custom synthesis services for N-Trifluoroacetamido-4'-p-nitrobenzoyl Daunorubicin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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