10-Hydroxyamitriptyline
TL;DR: 10-Hydroxyamitriptyline (CAS 72402-20-1) is a chemical compound with molecular formula C20H23NO and molecular weight 293.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[3-(dimethylamino)propylidene]tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-9-ol
Also Known As: 10-Hydroxyamitriptyline, hydroxyamitriptyline, Z-10-Hydroxyamitriptyline, AmitriptylineEP Impurity F, Amitriptyline EP Impurity F
| Molecular Formula | C20H23NO |
|---|---|
| Molecular Weight | 293.18 g/mol |
| LogP | 3.9 |
| Topological Polar Surface Area | 23.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 293.17798 |
| Heavy Atoms | 22 |
| Complexity | 389.0 |
Chemical Identifiers
| CAS Number | 72402-20-1 |
|---|---|
| SMILES | CN(C)CCC=C1C2=CC=CC=C2CC(C3=CC=CC=C31)O |
| InChIKey | GHWBJXOKAFHZAI-UHFFFAOYSA-N |
Product Overview
10-Hydroxyamitriptyline (CAS 72402-20-1), with molecular formula C20H23NO and molecular weight 293.18 g/mol. IUPAC: 2-[3-(dimethylamino)propylidene]tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-9-ol.
Chemical Property Profile of 10-Hydroxyamitriptyline
Property Insights of 10-Hydroxyamitriptyline
The XLogP value of 3.9 indicates that 10-Hydroxyamitriptyline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.5 Ų, 10-Hydroxyamitriptyline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 10-Hydroxyamitriptyline has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10-Hydroxyamitriptyline?
The CAS number of 10-Hydroxyamitriptyline is 72402-20-1.
What is the molecular formula of 10-Hydroxyamitriptyline?
The molecular formula of 10-Hydroxyamitriptyline is C20H23NO.
What is the molecular weight of 10-Hydroxyamitriptyline?
The molecular weight of 10-Hydroxyamitriptyline is 293.18 g/mol.
Where can I buy 10-Hydroxyamitriptyline?
You can request a quote for 10-Hydroxyamitriptyline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10-Hydroxyamitriptyline?
Yes, KEHONG BIO provides custom synthesis services for 10-Hydroxyamitriptyline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.