L-Trofosfamide
TL;DR: L-Trofosfamide (CAS 72282-84-9) is a chemical compound with molecular formula C9H18Cl3N2O2P and molecular weight 322.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R)-N,N,3-tris(2-chloroethyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine
Also Known As: L-Trofosfamide, Trofosfamide, (-)-Trofosphamide, (R)-N,N,3-Tris(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, 2H-1,3,2-Oxazaphosphorin-2-amine, N,N,3-tris(2-chloroethyl)tetrahydro-, 2-oxide, (R)-
| Molecular Formula | C9H18Cl3N2O2P |
|---|---|
| Molecular Weight | 322.02 g/mol |
| LogP | 2.8352 |
| Topological Polar Surface Area | 32.78 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 7 |
| Exact Mass | 322.01715 |
| Heavy Atoms | 17 |
| Complexity | 262.62552 |
Chemical Identifiers
| CAS Number | 72282-84-9 |
|---|---|
| SMILES | C1CN([P@@](=O)(OC1)N(CCCl)CCCl)CCCl |
Product Overview
L-Trofosfamide (CAS 72282-84-9), with molecular formula C9H18Cl3N2O2P and molecular weight 322.02 g/mol. IUPAC: (2R)-N,N,3-tris(2-chloroethyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine.
Chemical Property Profile of L-Trofosfamide
Property Insights of L-Trofosfamide
The XLogP value of 2.8352 suggests moderate lipophilicity, balancing water solubility and membrane permeability for L-Trofosfamide. With a topological polar surface area (TPSA) of 32.78 Ų, L-Trofosfamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, L-Trofosfamide has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of L-Trofosfamide?
The CAS number of L-Trofosfamide is 72282-84-9.
What is the molecular formula of L-Trofosfamide?
The molecular formula of L-Trofosfamide is C9H18Cl3N2O2P.
What is the molecular weight of L-Trofosfamide?
The molecular weight of L-Trofosfamide is 322.02 g/mol.
Where can I buy L-Trofosfamide?
You can request a quote for L-Trofosfamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for L-Trofosfamide?
Yes, KEHONG BIO provides custom synthesis services for L-Trofosfamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.