Methylene Blue Trihydrate structure

Methylene Blue Trihydrate

TL;DR: Methylene Blue Trihydrate (CAS 7220-79-3) is a chemical compound with molecular formula C16H24ClN3O3S and molecular weight 373.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate

Also Known As: methylene blue, Methylene Blue trihydrate, methyleneblue, Basic blue 9, Provayblue

CAS: 7220-79-3
Molecular Formula C16H24ClN3O3S
Molecular Weight 373.12 g/mol
LogP -2.97
Topological Polar Surface Area 46.9 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 7
Rotatable Bonds 1
Exact Mass 373.12268
Heavy Atoms 24
Complexity 483.0
Melting Point 190.0 °C (decomposes)
Solubility greater than or equal to 100 mg/mL at 72 °F (NTP, 1992)

Chemical Identifiers

CAS Number 7220-79-3
SMILES CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.O.O.O.[Cl-]
InChIKey XQAXGZLFSSPBMK-UHFFFAOYSA-M

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Analytical Reagents (5 patents) Coatings & Adhesives (5 patents) Textile Chemicals (1 patents)

Product Overview

Methylene Blue Trihydrate (CAS 7220-79-3), with molecular formula C16H24ClN3O3S and molecular weight 373.12 g/mol. IUPAC: [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Methylene Blue Trihydrate

XLogP
-2.97
TPSA (Topological Polar Surface Area)
46.9
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
7
Rotatable Bonds
1
Heavy Atoms
24
Complexity
483.0
Exact Mass
373.12268
Monoisotopic Mass
373.12268
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Methylene Blue Trihydrate

The XLogP value of -2.97 indicates that Methylene Blue Trihydrate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 46.9 Ų, Methylene Blue Trihydrate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Methylene Blue Trihydrate has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Methylene Blue Trihydrate?

The CAS number of Methylene Blue Trihydrate is 7220-79-3.

What is the molecular formula of Methylene Blue Trihydrate?

The molecular formula of Methylene Blue Trihydrate is C16H24ClN3O3S.

What is the molecular weight of Methylene Blue Trihydrate?

The molecular weight of Methylene Blue Trihydrate is 373.12 g/mol.

Where can I buy Methylene Blue Trihydrate?

You can request a quote for Methylene Blue Trihydrate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Methylene Blue Trihydrate?

Yes, KEHONG BIO provides custom synthesis services for Methylene Blue Trihydrate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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