4-((2-Chloro-6-fluorobenzyl)thio)quinazoline
TL;DR: 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline (CAS 721893-85-2) is a chemical compound with molecular formula C15H10ClFN2S and molecular weight 304.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[(2-chloro-6-fluorophenyl)methylsulfanyl]quinazoline
Also Known As: IFLab1_003477, 4-((2-chloro-6-fluorobenzyl)thio)quinazoline, F0674-0111, 4-[(2-chloro-6-fluorobenzyl)sulfanyl]quinazoline, 4-[(2-chloro-6-fluorophenyl)methylsulfanyl]quinazoline
| Molecular Formula | C15H10ClFN2S |
|---|---|
| Molecular Weight | 304.02 g/mol |
| LogP | 4.7146 |
| Topological Polar Surface Area | 25.78 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 304.0237 |
| Heavy Atoms | 20 |
| Complexity | 738.19965 |
Chemical Identifiers
| CAS Number | 721893-85-2 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=NC=N2)SCC3=C(C=CC=C3Cl)F |
Product Overview
4-((2-Chloro-6-fluorobenzyl)thio)quinazoline (CAS 721893-85-2), with molecular formula C15H10ClFN2S and molecular weight 304.02 g/mol. IUPAC: 4-[(2-chloro-6-fluorophenyl)methylsulfanyl]quinazoline.
Chemical Property Profile of 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline
Property Insights of 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline
The XLogP value of 4.7146 indicates that 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 25.78 Ų, 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline?
The CAS number of 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline is 721893-85-2.
What is the molecular formula of 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline?
The molecular formula of 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline is C15H10ClFN2S.
What is the molecular weight of 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline?
The molecular weight of 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline is 304.02 g/mol.
Where can I buy 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline?
You can request a quote for 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline?
Yes, KEHONG BIO provides custom synthesis services for 4-((2-Chloro-6-fluorobenzyl)thio)quinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.