Losulazine
TL;DR: Losulazine (CAS 72141-57-2) is a chemical compound with molecular formula C27H22F4N4O3S and molecular weight 558.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-(4-fluorophenyl)sulfonylpiperazin-1-yl]-[4-[[7-(trifluoromethyl)quinolin-4-yl]amino]phenyl]methanone
Also Known As: Losulazine, Losulazina, Losulazinum, Losulazine [INN], Losulazinum [Latin]
| Molecular Formula | C27H22F4N4O3S |
|---|---|
| Molecular Weight | 558.13 g/mol |
| LogP | 4.8 |
| Topological Polar Surface Area | 91.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 5 |
| Exact Mass | 558.1349 |
| Heavy Atoms | 39 |
| Complexity | 938.0 |
Chemical Identifiers
| CAS Number | 72141-57-2 |
|---|---|
| SMILES | C1CN(CCN1C(=O)C2=CC=C(C=C2)NC3=C4C=CC(=CC4=NC=C3)C(F)(F)F)S(=O)(=O)C5=CC=C(C=C5)F |
| InChIKey | SYJKIRZBDWNJSB-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Losulazine (CAS 72141-57-2), with molecular formula C27H22F4N4O3S and molecular weight 558.13 g/mol. IUPAC: [4-(4-fluorophenyl)sulfonylpiperazin-1-yl]-[4-[[7-(trifluoromethyl)quinolin-4-yl]amino]phenyl]methanone.
Chemical Property Profile of Losulazine
Property Insights of Losulazine
The XLogP value of 4.8 indicates that Losulazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 91.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Losulazine. Following Lipinski's Rule of Five, Losulazine has 1 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Losulazine?
The CAS number of Losulazine is 72141-57-2.
What is the molecular formula of Losulazine?
The molecular formula of Losulazine is C27H22F4N4O3S.
What is the molecular weight of Losulazine?
The molecular weight of Losulazine is 558.13 g/mol.
Where can I buy Losulazine?
You can request a quote for Losulazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Losulazine?
Yes, KEHONG BIO provides custom synthesis services for Losulazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.