4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester
TL;DR: 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester (CAS 721399-93-5) is a chemical compound with molecular formula C18H13Cl2NO2S and molecular weight 377.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl 4,5-bis(4-chlorophenyl)-1,3-thiazole-2-carboxylate
Also Known As: 4,5-bis-(4-chloro-phenyl)-thiazole-2-carboxylic acid ethyl ester, Ethyl 4,5-bis(4-chlorophenyl)-1,3-thiazole-2-carboxylate, 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester
| Molecular Formula | C18H13Cl2NO2S |
|---|---|
| Molecular Weight | 377.00 g/mol |
| LogP | 5.9606 |
| Topological Polar Surface Area | 39.19 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 377.0044 |
| Heavy Atoms | 24 |
| Complexity | 794.7302 |
Chemical Identifiers
| CAS Number | 721399-93-5 |
|---|---|
| SMILES | CCOC(=O)C1=NC(=C(S1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Cl |
Product Overview
4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester (CAS 721399-93-5), with molecular formula C18H13Cl2NO2S and molecular weight 377.00 g/mol. IUPAC: ethyl 4,5-bis(4-chlorophenyl)-1,3-thiazole-2-carboxylate.
Chemical Property Profile of 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester
Property Insights of 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester
The XLogP value of 5.9606 indicates that 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 39.19 Ų, 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester?
The CAS number of 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester is 721399-93-5.
What is the molecular formula of 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester?
The molecular formula of 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester is C18H13Cl2NO2S.
What is the molecular weight of 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester?
The molecular weight of 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester is 377.00 g/mol.
Where can I buy 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester?
You can request a quote for 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester?
Yes, KEHONG BIO provides custom synthesis services for 4,5-Bis-(4-chlorophenyl)thiazole-2-carboxylic acid ethyl ester and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.