![N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide structure](/static/products/720/720677-50-9.png)
N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide
TL;DR: N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide (CAS 720677-50-9) is a chemical compound with molecular formula C13H8ClF3N2O and molecular weight 300.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[5-chloro-2-(trifluoromethyl)phenyl]pyridine-4-carboxamide
Also Known As: N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide, AE-848/11247405, N-[5-chloro-2-(trifluoromethyl)phenyl]pyridine-4-carboxamide
| Molecular Formula | C13H8ClF3N2O |
|---|---|
| Molecular Weight | 300.03 g/mol |
| LogP | 4.0061 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 300.0277 |
| Heavy Atoms | 20 |
| Complexity | 629.25854 |
Chemical Identifiers
| CAS Number | 720677-50-9 |
|---|---|
| SMILES | C1=CC(=C(C=C1Cl)NC(=O)C2=CC=NC=C2)C(F)(F)F |
Product Overview
N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide (CAS 720677-50-9), with molecular formula C13H8ClF3N2O and molecular weight 300.03 g/mol. IUPAC: N-[5-chloro-2-(trifluoromethyl)phenyl]pyridine-4-carboxamide.
Chemical Property Profile of N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide
Property Insights of N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide
The XLogP value of 4.0061 indicates that N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide?
The CAS number of N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide is 720677-50-9.
What is the molecular formula of N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide?
The molecular formula of N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide is C13H8ClF3N2O.
What is the molecular weight of N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide?
The molecular weight of N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide is 300.03 g/mol.
Where can I buy N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide?
You can request a quote for N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide?
Yes, KEHONG BIO provides custom synthesis services for N-[5-chloro-2-(trifluoromethyl)phenyl]isonicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.