4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone
TL;DR: 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone (CAS 720676-01-7) is a chemical compound with molecular formula C17H15FO4 and molecular weight 302.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(4-fluorophenyl)-1-(2-hydroxy-4,6-dimethoxyphenyl)prop-2-en-1-one
Also Known As: 4',6'-DIMETHOXY-4-FLUORO-2'-HYDROXYCHALCONE, J2.130.743B, 3-(4-fluorophenyl)-1-(2-hydroxy-4,6-dimethoxyphenyl)-2-propen-1-one, 4/',6/'-Dimethoxy-4-fluoro-2/'-hydroxychalcone, AQ-358/42003073
| Molecular Formula | C17H15FO4 |
|---|---|
| Molecular Weight | 302.10 g/mol |
| LogP | 3.4446 |
| Topological Polar Surface Area | 55.76 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 302.09543 |
| Heavy Atoms | 22 |
| Complexity | 705.34406 |
Chemical Identifiers
| CAS Number | 720676-01-7 |
|---|---|
| SMILES | COC1=CC(=C(C(=C1)OC)C(=O)/C=C/C2=CC=C(C=C2)F)O |
Product Overview
4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone (CAS 720676-01-7), with molecular formula C17H15FO4 and molecular weight 302.10 g/mol. IUPAC: (E)-3-(4-fluorophenyl)-1-(2-hydroxy-4,6-dimethoxyphenyl)prop-2-en-1-one.
Chemical Property Profile of 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone
Property Insights of 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone
The XLogP value of 3.4446 indicates that 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.76 Ų, 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone?
The CAS number of 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone is 720676-01-7.
What is the molecular formula of 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone?
The molecular formula of 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone is C17H15FO4.
What is the molecular weight of 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone?
The molecular weight of 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone is 302.10 g/mol.
Where can I buy 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone?
You can request a quote for 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone?
Yes, KEHONG BIO provides custom synthesis services for 4',6'-Dimethoxy-4-fluoro-2'-hydroxychalcone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.