(4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone
TL;DR: (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone (CAS 717872-46-3) is a chemical compound with molecular formula C20H20N4OS and molecular weight 364.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4-methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone
Also Known As: (4-methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone, 4-methyl-5-phenyl(2-thienyl) 4-pyrimidin-2-ylpiperazinyl ketone, 2-{4-[(4-methyl-5-phenyl-2-thienyl)carbonyl]-1-piperazinyl}pyrimidine, (4-METHYL-5-PHENYL-2-THIENYL)[4-(2-PYRIMIDINYL)PIPERAZINO]METHANONE, (4-methyl-5-phenylthiophen-2-yl)[4-(pyrimidin-2-yl)piperazin-1-yl]methanone
| Molecular Formula | C20H20N4OS |
|---|---|
| Molecular Weight | 364.14 g/mol |
| LogP | 3.47592 |
| Topological Polar Surface Area | 49.33 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 364.13577 |
| Heavy Atoms | 26 |
| Complexity | 886.68933 |
Chemical Identifiers
| CAS Number | 717872-46-3 |
|---|---|
| SMILES | CC1=C(SC(=C1)C(=O)N2CCN(CC2)C3=NC=CC=N3)C4=CC=CC=C4 |
Product Overview
(4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone (CAS 717872-46-3), with molecular formula C20H20N4OS and molecular weight 364.14 g/mol. IUPAC: (4-methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone.
Chemical Property Profile of (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone
Property Insights of (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone
The XLogP value of 3.47592 indicates that (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.33 Ų, (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone?
The CAS number of (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone is 717872-46-3.
What is the molecular formula of (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone?
The molecular formula of (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone is C20H20N4OS.
What is the molecular weight of (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone?
The molecular weight of (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone is 364.14 g/mol.
Where can I buy (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone?
You can request a quote for (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone?
Yes, KEHONG BIO provides custom synthesis services for (4-Methyl-5-phenylthiophen-2-yl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.