Ampicillin Trihydrate
TL;DR: Ampicillin Trihydrate (CAS 7177-48-2) is a chemical compound with molecular formula C16H25N3O7S and molecular weight 403.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;trihydrate
Also Known As: AMPICILLIN TRIHYDRATE, ampicillin, Polycillin, Trafarbiot, Principen
| Molecular Formula | C16H25N3O7S |
|---|---|
| Molecular Weight | 403.14 g/mol |
| LogP | -2.16 |
| Topological Polar Surface Area | 141.0 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 4 |
| Exact Mass | 403.14133 |
| Heavy Atoms | 27 |
| Complexity | 562.0 |
| Melting Point | 388 to 200.0 °C (decomposes) |
| Solubility | 1 to 10 mg/mL at 70 °F (NTP, 1992) |
Chemical Identifiers
| CAS Number | 7177-48-2 |
|---|---|
| SMILES | CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)O)C.O.O.O |
| InChIKey | RXDALBZNGVATNY-CWLIKTDRSA-N |
Patent-Derived Application Labels
Derived from 18 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Ampicillin Trihydrate (CAS 7177-48-2), with molecular formula C16H25N3O7S and molecular weight 403.14 g/mol. IUPAC: (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;trihydrate.
Chemical Property Profile of Ampicillin Trihydrate
Property Insights of Ampicillin Trihydrate
The XLogP value of -2.16 indicates that Ampicillin Trihydrate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 141.0 Ų indicates high polarity, suggesting Ampicillin Trihydrate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Ampicillin Trihydrate has 6 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ampicillin Trihydrate?
The CAS number of Ampicillin Trihydrate is 7177-48-2.
What is the molecular formula of Ampicillin Trihydrate?
The molecular formula of Ampicillin Trihydrate is C16H25N3O7S.
What is the molecular weight of Ampicillin Trihydrate?
The molecular weight of Ampicillin Trihydrate is 403.14 g/mol.
Where can I buy Ampicillin Trihydrate?
You can request a quote for Ampicillin Trihydrate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ampicillin Trihydrate?
Yes, KEHONG BIO provides custom synthesis services for Ampicillin Trihydrate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.