Irazepine structure

Irazepine

TL;DR: Irazepine (CAS 71735-92-7) is a chemical compound with molecular formula C18H13ClFN3OS and molecular weight 373.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

7-chloro-5-(2-fluorophenyl)-1-(2-isothiocyanatoethyl)-3H-1,4-benzodiazepin-2-one

Also Known As: Irazepine, 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2-isothiocyanatoethyl)-, 1-(2-Isothiocyantoethyl)-7-chloro-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepine-2-one, 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2-isothiocyanatoethyl)-2H-1,4-benzodiazepin-2-one, 7-chloro-5-(2-fluorophenyl)-1-(2-isothiocyanatoethyl)-3H-1,4-benzodiazepin-2-one

CAS: 71735-92-7
Molecular Formula C18H13ClFN3OS
Molecular Weight 373.05 g/mol
LogP 3.6
Topological Polar Surface Area 77.1 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 5
Rotatable Bonds 4
Exact Mass 373.0452
Heavy Atoms 25
Complexity 581.0

Chemical Identifiers

CAS Number 71735-92-7
SMILES C1C(=O)N(C2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F)CCN=C=S
InChIKey LTKSVYFAUMFQML-UHFFFAOYSA-N

Product Overview

Irazepine (CAS 71735-92-7), with molecular formula C18H13ClFN3OS and molecular weight 373.05 g/mol. IUPAC: 7-chloro-5-(2-fluorophenyl)-1-(2-isothiocyanatoethyl)-3H-1,4-benzodiazepin-2-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Irazepine

XLogP
3.6
TPSA (Topological Polar Surface Area)
77.1
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
5
Rotatable Bonds
4
Heavy Atoms
25
Complexity
581.0
Exact Mass
373.0452
Monoisotopic Mass
373.0452
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Irazepine

The XLogP value of 3.6 indicates that Irazepine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Irazepine. Following Lipinski's Rule of Five, Irazepine has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Irazepine?

The CAS number of Irazepine is 71735-92-7.

What is the molecular formula of Irazepine?

The molecular formula of Irazepine is C18H13ClFN3OS.

What is the molecular weight of Irazepine?

The molecular weight of Irazepine is 373.05 g/mol.

Where can I buy Irazepine?

You can request a quote for Irazepine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Irazepine?

Yes, KEHONG BIO provides custom synthesis services for Irazepine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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