Loflazepic acid structure

Loflazepic acid

TL;DR: Loflazepic acid (CAS 71735-10-9) is a chemical compound with molecular formula C16H10ClFN2O3 and molecular weight 332.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

Loflazepic acid

7-chloro-5-(2-fluorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepine-3-carboxylic acid

Also Known As: Loflazepic acid, LOFLAZEPATE, (+/-)-LOFLAZEPIC ACID, CM 6913, 7-Chloro-5-(2-fluorophenyl) 2,3-dihydro-2-oxo-1H-1,4-benzodiazepine-3-carboxylic acid

CAS: 71735-10-9
Molecular Formula C16H10ClFN2O3
Molecular Weight 332.04 g/mol
LogP 2.8
Topological Polar Surface Area 78.8 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 5
Rotatable Bonds 2
Exact Mass 332.0364
Heavy Atoms 23
Complexity 527.0

Chemical Identifiers

CAS Number 71735-10-9
SMILES C1=CC=C(C(=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)C(=O)O)F
InChIKey AUMAPAHSHLMFGL-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (3 patents)

Product Overview

Loflazepic acid (CAS 71735-10-9), with molecular formula C16H10ClFN2O3 and molecular weight 332.04 g/mol. IUPAC: 7-chloro-5-(2-fluorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepine-3-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Loflazepic acid

XLogP
2.8
TPSA (Topological Polar Surface Area)
78.8
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
5
Rotatable Bonds
2
Heavy Atoms
23
Complexity
527.0
Exact Mass
332.0364
Monoisotopic Mass
332.0364
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Loflazepic acid

The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Loflazepic acid. The TPSA of 78.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Loflazepic acid. Following Lipinski's Rule of Five, Loflazepic acid has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Loflazepic acid?

The CAS number of Loflazepic acid is 71735-10-9.

What is the molecular formula of Loflazepic acid?

The molecular formula of Loflazepic acid is C16H10ClFN2O3.

What is the molecular weight of Loflazepic acid?

The molecular weight of Loflazepic acid is 332.04 g/mol.

Where can I buy Loflazepic acid?

You can request a quote for Loflazepic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Loflazepic acid?

Yes, KEHONG BIO provides custom synthesis services for Loflazepic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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