N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide
TL;DR: N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide (CAS 7168-08-3) is a chemical compound with molecular formula C17H11ClF2N2O3S and molecular weight 396.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)-1-benzothiophene-2-carboxamide
Also Known As: N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide, N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)-1-benzothiophene-2-carboxamide, N-[2-(AMINOCARBONYL)PHENYL]-3-CHLORO-4-(DIFLUOROMETHOXY)-1-BENZOTHIOPHENE-2-CARBOXAMIDE
| Molecular Formula | C17H11ClF2N2O3S |
|---|---|
| Molecular Weight | 396.01 g/mol |
| LogP | 4.5073 |
| Topological Polar Surface Area | 81.42 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 396.0147 |
| Heavy Atoms | 26 |
| Complexity | 1006.83673 |
Chemical Identifiers
| CAS Number | 7168-08-3 |
|---|---|
| SMILES | C1=CC=C(C(=C1)C(=O)N)NC(=O)C2=C(C3=C(C=CC=C3S2)OC(F)F)Cl |
Product Overview
N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide (CAS 7168-08-3), with molecular formula C17H11ClF2N2O3S and molecular weight 396.01 g/mol. IUPAC: N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)-1-benzothiophene-2-carboxamide.
Chemical Property Profile of N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide
Property Insights of N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide
The XLogP value of 4.5073 indicates that N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.42 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide. Following Lipinski's Rule of Five, N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide?
The CAS number of N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide is 7168-08-3.
What is the molecular formula of N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide?
The molecular formula of N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide is C17H11ClF2N2O3S.
What is the molecular weight of N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide?
The molecular weight of N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide is 396.01 g/mol.
Where can I buy N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide?
You can request a quote for N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-(2-carbamoylphenyl)-3-chloro-4-(difluoromethoxy)benzothiophene-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.