Riodipine
TL;DR: Riodipine (CAS 71653-63-9) is a chemical compound with molecular formula C18H19F2NO5 and molecular weight 367.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
dimethyl 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Riodipine, Ryodipine, Foridon, Riodipino, Riodipinum
| Molecular Formula | C18H19F2NO5 |
|---|---|
| Molecular Weight | 367.12 g/mol |
| LogP | 3.3 |
| Topological Polar Surface Area | 73.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 7 |
| Exact Mass | 367.12314 |
| Heavy Atoms | 26 |
| Complexity | 591.0 |
Chemical Identifiers
| CAS Number | 71653-63-9 |
|---|---|
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2OC(F)F)C(=O)OC |
| InChIKey | AZVFIZVKGSPGPK-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Riodipine (CAS 71653-63-9), with molecular formula C18H19F2NO5 and molecular weight 367.12 g/mol. IUPAC: dimethyl 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of Riodipine
Property Insights of Riodipine
The XLogP value of 3.3 indicates that Riodipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 73.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Riodipine. Following Lipinski's Rule of Five, Riodipine has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Riodipine?
The CAS number of Riodipine is 71653-63-9.
What is the molecular formula of Riodipine?
The molecular formula of Riodipine is C18H19F2NO5.
What is the molecular weight of Riodipine?
The molecular weight of Riodipine is 367.12 g/mol.
Where can I buy Riodipine?
You can request a quote for Riodipine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Riodipine?
Yes, KEHONG BIO provides custom synthesis services for Riodipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.