24,24-difluoro-25-hydroxyvitamin D3 structure

24,24-difluoro-25-hydroxyvitamin D3

TL;DR: 24,24-difluoro-25-hydroxyvitamin D3 (CAS 71603-41-3) is a chemical compound with molecular formula C27H42F2O2 and molecular weight 436.32 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(1R,3Z)-3-[(2E)-2-[(3aS,7aR)-1-[(2R)-5,5-difluoro-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol

Also Known As: 24,24-Dfhv, 24,24-Difluoro-25-hydroxyvitamin D3, 24,24-Difluoro-25-hydroxycholecalciferol, (1R,3Z)-3-[(2E)-2-[(3aS,7aR)-1-[(2R)-5,5-difluoro-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol, 9,10-Secocholesta-5,7,10(19)-triene-3,25-diol, 24,24-difluoro-, (3beta,5Z,7E)-

CAS: 71603-41-3
Molecular Formula C27H42F2O2
Molecular Weight 436.32 g/mol
LogP 6.9791
Topological Polar Surface Area 40.46 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 2
Rotatable Bonds 6
Exact Mass 436.31528
Heavy Atoms 31
Complexity 730.00867

Chemical Identifiers

CAS Number 71603-41-3
SMILES C[C@H](CCC(C(C)(C)O)(F)F)C1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@@H](CCC3=C)O)C

Product Overview

24,24-difluoro-25-hydroxyvitamin D3 (CAS 71603-41-3), with molecular formula C27H42F2O2 and molecular weight 436.32 g/mol. IUPAC: (1R,3Z)-3-[(2E)-2-[(3aS,7aR)-1-[(2R)-5,5-difluoro-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 24,24-difluoro-25-hydroxyvitamin D3

XLogP
6.9791
TPSA (Topological Polar Surface Area)
40.46
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
2
Rotatable Bonds
6
Heavy Atoms
31
Complexity
730.00867
Exact Mass
436.31528
Monoisotopic Mass
436.31528
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 24,24-difluoro-25-hydroxyvitamin D3

The XLogP value of 6.9791 indicates that 24,24-difluoro-25-hydroxyvitamin D3 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.46 Ų, 24,24-difluoro-25-hydroxyvitamin D3 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 24,24-difluoro-25-hydroxyvitamin D3 has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 24,24-difluoro-25-hydroxyvitamin D3?

The CAS number of 24,24-difluoro-25-hydroxyvitamin D3 is 71603-41-3.

What is the molecular formula of 24,24-difluoro-25-hydroxyvitamin D3?

The molecular formula of 24,24-difluoro-25-hydroxyvitamin D3 is C27H42F2O2.

What is the molecular weight of 24,24-difluoro-25-hydroxyvitamin D3?

The molecular weight of 24,24-difluoro-25-hydroxyvitamin D3 is 436.32 g/mol.

Where can I buy 24,24-difluoro-25-hydroxyvitamin D3?

You can request a quote for 24,24-difluoro-25-hydroxyvitamin D3 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 24,24-difluoro-25-hydroxyvitamin D3?

Yes, KEHONG BIO provides custom synthesis services for 24,24-difluoro-25-hydroxyvitamin D3 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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