(E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole
TL;DR: (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole (CAS 714930-35-5) is a chemical compound with molecular formula C21H20ClFN4O2S2 and molecular weight 478.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]-4-(3-piperidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine
Also Known As: (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole, 1-[(3-{(2Z)-2-[(2E)-(2-chloro-6-fluorobenzylidene)hydrazinylidene]-2,3-dihydro-1,3-thiazol-4-yl}phenyl)sulfonyl]piperidine, N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]-4-(3-piperidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine
| Molecular Formula | C21H20ClFN4O2S2 |
|---|---|
| Molecular Weight | 478.07 g/mol |
| LogP | 5.2232 |
| Topological Polar Surface Area | 74.66 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 478.07004 |
| Heavy Atoms | 31 |
| Complexity | 1187.3438 |
Chemical Identifiers
| CAS Number | 714930-35-5 |
|---|---|
| SMILES | C1CCN(CC1)S(=O)(=O)C2=CC=CC(=C2)C3=CSC(=N3)N/N=C/C4=C(C=CC=C4Cl)F |
Product Overview
(E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole (CAS 714930-35-5), with molecular formula C21H20ClFN4O2S2 and molecular weight 478.07 g/mol. IUPAC: N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]-4-(3-piperidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine.
Chemical Property Profile of (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole
Property Insights of (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole
The XLogP value of 5.2232 indicates that (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 74.66 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole. Following Lipinski's Rule of Five, (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole?
The CAS number of (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole is 714930-35-5.
What is the molecular formula of (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole?
The molecular formula of (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole is C21H20ClFN4O2S2.
What is the molecular weight of (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole?
The molecular weight of (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole is 478.07 g/mol.
Where can I buy (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole?
You can request a quote for (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-(2-(2-chloro-6-fluorobenzylidene)hydrazinyl)-4-(3-(piperidin-1-ylsulfonyl)phenyl)thiazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.