NCIOpen2_004131 structure

NCIOpen2_004131

TL;DR: NCIOpen2_004131 (CAS 7144-25-4) is a chemical compound with molecular formula C10H6Cl2N2O2S and molecular weight 287.95 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-(2,4-dichlorophenoxy)-2-sulfanylidene-1H-pyrimidin-4-one

Also Known As: NCIOpen2_004131, 5-(2,4-dichlorophenoxy)-2-sulfanylidene-1H-pyrimidin-4-one, 5-(2,4-dichlorophenoxy)-2-thioxo-1H-pyrimidin-4-one, 5-[2,4-bis(chloranyl)phenoxy]-2-sulfanylidene-1H-pyrimidin-4-one, 5-(2,4-Dichlorophenoxy)-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one

CAS: 7144-25-4
Molecular Formula C10H6Cl2N2O2S
Molecular Weight 287.95 g/mol
LogP 3.53159
Topological Polar Surface Area 57.88 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 3
Rotatable Bonds 2
Exact Mass 287.9527
Heavy Atoms 17
Complexity 665.8409

Chemical Identifiers

CAS Number 7144-25-4
SMILES C1=CC(=C(C=C1Cl)Cl)OC2=CNC(=S)NC2=O

Product Overview

NCIOpen2_004131 (CAS 7144-25-4), with molecular formula C10H6Cl2N2O2S and molecular weight 287.95 g/mol. IUPAC: 5-(2,4-dichlorophenoxy)-2-sulfanylidene-1H-pyrimidin-4-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of NCIOpen2_004131

XLogP
3.53159
TPSA (Topological Polar Surface Area)
57.88
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
3
Rotatable Bonds
2
Heavy Atoms
17
Complexity
665.8409
Exact Mass
287.9527
Monoisotopic Mass
287.9527
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of NCIOpen2_004131

The XLogP value of 3.53159 indicates that NCIOpen2_004131 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.88 Ų, NCIOpen2_004131 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, NCIOpen2_004131 has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of NCIOpen2_004131?

The CAS number of NCIOpen2_004131 is 7144-25-4.

What is the molecular formula of NCIOpen2_004131?

The molecular formula of NCIOpen2_004131 is C10H6Cl2N2O2S.

What is the molecular weight of NCIOpen2_004131?

The molecular weight of NCIOpen2_004131 is 287.95 g/mol.

Where can I buy NCIOpen2_004131?

You can request a quote for NCIOpen2_004131 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for NCIOpen2_004131?

Yes, KEHONG BIO provides custom synthesis services for NCIOpen2_004131 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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