Plinabulin
TL;DR: Plinabulin (CAS 714272-27-2) is a chemical compound with molecular formula C19H20N4O2 and molecular weight 336.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione
Also Known As: Plinabulin, plinabulina, plinabuline, plinabulinum, Plinabulin?
| Molecular Formula | C19H20N4O2 |
|---|---|
| Molecular Weight | 336.16 g/mol |
| LogP | 0.7414 |
| Topological Polar Surface Area | 94.4 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 336.15863 |
| Heavy Atoms | 25 |
| Complexity | 1112.9564 |
Chemical Identifiers
| CAS Number | 714272-27-2 |
|---|---|
| SMILES | CC(C)(C)C1=C(N=CN1)/C=C\2/C(=O)N/C(=C\C3=CC=CC=C3)/C(=O)N2 |
Product Overview
Plinabulin (CAS 714272-27-2), with molecular formula C19H20N4O2 and molecular weight 336.16 g/mol. IUPAC: (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione.
Chemical Property Profile of Plinabulin
Property Insights of Plinabulin
The XLogP value of 0.7414 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Plinabulin. The TPSA of 94.4 Ų falls within the moderate polarity range, balancing permeability and solubility for Plinabulin. Following Lipinski's Rule of Five, Plinabulin has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Plinabulin?
The CAS number of Plinabulin is 714272-27-2.
What is the molecular formula of Plinabulin?
The molecular formula of Plinabulin is C19H20N4O2.
What is the molecular weight of Plinabulin?
The molecular weight of Plinabulin is 336.16 g/mol.
Where can I buy Plinabulin?
You can request a quote for Plinabulin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Plinabulin?
Yes, KEHONG BIO provides custom synthesis services for Plinabulin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.