Lotifazole
TL;DR: Lotifazole (CAS 71119-10-3) is a chemical compound with molecular formula C12H9Cl3N2O2S and molecular weight 349.95 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,2,2-trichloroethyl N-(4-phenyl-1,3-thiazol-2-yl)carbamate
Also Known As: Lotifazole, Lotifazol, Lotifazolum, Lotifazole [INN], Lotifazol [INN-Spanish]
| Molecular Formula | C12H9Cl3N2O2S |
|---|---|
| Molecular Weight | 349.95 g/mol |
| LogP | 4.4 |
| Topological Polar Surface Area | 79.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 349.94504 |
| Heavy Atoms | 20 |
| Complexity | 335.0 |
Chemical Identifiers
| CAS Number | 71119-10-3 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=CSC(=N2)NC(=O)OCC(Cl)(Cl)Cl |
| InChIKey | SMQXDOVGKKMUIZ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Lotifazole (CAS 71119-10-3), with molecular formula C12H9Cl3N2O2S and molecular weight 349.95 g/mol. IUPAC: 2,2,2-trichloroethyl N-(4-phenyl-1,3-thiazol-2-yl)carbamate.
Chemical Property Profile of Lotifazole
Property Insights of Lotifazole
The XLogP value of 4.4 indicates that Lotifazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Lotifazole. Following Lipinski's Rule of Five, Lotifazole has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lotifazole?
The CAS number of Lotifazole is 71119-10-3.
What is the molecular formula of Lotifazole?
The molecular formula of Lotifazole is C12H9Cl3N2O2S.
What is the molecular weight of Lotifazole?
The molecular weight of Lotifazole is 349.95 g/mol.
Where can I buy Lotifazole?
You can request a quote for Lotifazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lotifazole?
Yes, KEHONG BIO provides custom synthesis services for Lotifazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.