![(10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one structure](/static/products/710/710304-73-7.png)
(10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one
TL;DR: (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one (CAS 710304-73-7) is a chemical compound with molecular formula C32H23FN2O2S and molecular weight 518.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(14Z)-11-(4-fluorophenyl)-14-[(2-methoxynaphthalen-1-yl)methylidene]-15-thia-12,17-diazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,16-pentaen-13-one
Also Known As: (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one, (Z)-7-(4-fluorophenyl)-10-((2-methoxynaphthalen-1-yl)methylene)-7,10-dihydro-5H-benzo[h]thiazolo[2,3-b]quinazolin-9(6H)-one, 7-(4-fluorophenyl)-10-[(2-methoxynaphthyl)methylene]-5,6,7,8-tetrahydrobenzo[h ]1,3-thiazolidino[2,3-b]quinazolin-9-one
| Molecular Formula | C32H23FN2O2S |
|---|---|
| Molecular Weight | 518.15 g/mol |
| LogP | 5.6196 |
| Topological Polar Surface Area | 43.59 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 518.1464 |
| Heavy Atoms | 38 |
| Complexity | 1950.6384 |
Chemical Identifiers
| CAS Number | 710304-73-7 |
|---|---|
| SMILES | COC1=C(C2=CC=CC=C2C=C1)/C=C\3/C(=O)N4C(C5=C(C6=CC=CC=C6CC5)N=C4S3)C7=CC=C(C=C7)F |
Product Overview
(10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one (CAS 710304-73-7), with molecular formula C32H23FN2O2S and molecular weight 518.15 g/mol. IUPAC: (14Z)-11-(4-fluorophenyl)-14-[(2-methoxynaphthalen-1-yl)methylidene]-15-thia-12,17-diazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,16-pentaen-13-one.
Chemical Property Profile of (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one
Property Insights of (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one
The XLogP value of 5.6196 indicates that (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 43.59 Ų, (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one?
The CAS number of (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one is 710304-73-7.
What is the molecular formula of (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one?
The molecular formula of (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one is C32H23FN2O2S.
What is the molecular weight of (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one?
The molecular weight of (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one is 518.15 g/mol.
Where can I buy (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one?
You can request a quote for (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one?
Yes, KEHONG BIO provides custom synthesis services for (10Z)-7-(4-fluorophenyl)-10-[(2-methoxynaphthalen-1-yl)methylidene]-5,7-dihydro-6H-benzo[h][1,3]thiazolo[2,3-b]quinazolin-9(10H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.