Doxazosin, (R)-
TL;DR: Doxazosin, (R)- (CAS 70918-17-1) is a chemical compound with molecular formula C23H25N5O5 and molecular weight 451.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methanone
Also Known As: R-Doxazosin, doxazosin, Doxazosin, (R)-, (R)-Doxazosin, (-)-(R)-Doxazosin
| Molecular Formula | C23H25N5O5 |
|---|---|
| Molecular Weight | 451.19 g/mol |
| LogP | 1.7178 |
| Topological Polar Surface Area | 112.27 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 4 |
| Exact Mass | 451.18558 |
| Heavy Atoms | 33 |
| Complexity | 1195.3208 |
Chemical Identifiers
| CAS Number | 70918-17-1 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)[C@H]4COC5=CC=CC=C5O4)N)OC |
Product Overview
Doxazosin, (R)- (CAS 70918-17-1), with molecular formula C23H25N5O5 and molecular weight 451.19 g/mol. IUPAC: [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methanone.
Chemical Property Profile of Doxazosin, (R)-
Property Insights of Doxazosin, (R)-
The XLogP value of 1.7178 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Doxazosin, (R)-. The TPSA of 112.27 Ų falls within the moderate polarity range, balancing permeability and solubility for Doxazosin, (R)-. Following Lipinski's Rule of Five, Doxazosin, (R)- has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Doxazosin, (R)-?
The CAS number of Doxazosin, (R)- is 70918-17-1.
What is the molecular formula of Doxazosin, (R)-?
The molecular formula of Doxazosin, (R)- is C23H25N5O5.
What is the molecular weight of Doxazosin, (R)-?
The molecular weight of Doxazosin, (R)- is 451.19 g/mol.
Where can I buy Doxazosin, (R)-?
You can request a quote for Doxazosin, (R)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Doxazosin, (R)-?
Yes, KEHONG BIO provides custom synthesis services for Doxazosin, (R)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.